Orthopedic Implants in Minnesota

Ilion Medical Inc manufactures sacroiliac joint fusion implants. The company's primary product is the NADIA® implant system, a threaded titanium cage designed for sacroiliac joint fusion using a postero-medial surgical approach. The NADIA® system incorporates NeuroSafe® technology, indicating a focus on neurological protection during implantation. The implant is engineered to remain safely within bone, addressing chronic sacroiliac joint dysfunction and pain. The company serves orthopedic surgeons and spine surgery centers specializing in sacroiliac joint pathology. Product development emphasizes surgical technique refinement and implant design optimization for this specific spinal fusion indication.

ADCURA, INC. is a medical device company specializing in innovative spine surgery solutions. The company develops and markets the Sagittae® Lateral Lumbar Interbody Fusion (LLIF) System, a differentiated first-to-market technology designed to improve surgical outcomes for patients with spine-related conditions. The Sagittae® system features fully adjustable, expandable technology with 2-degree-of-freedom capability, enabling patient-specific surgical solutions that maximize surgical efficiency while minimizing post-operative complications. The technology is designed to streamline surgical inventory management and address current inefficiencies in spinal fusion procedures. ADCURA focuses on precise patient solutions that improve quality of life for individuals suffering from lumbar spine pathology. The company provides comprehensive surgical documentation including Instructions for Use, product brochures, and validated surgical technique guidance. Products are supported by patent and trademark protections. ADCURA serves spine surgeons and surgical centers seeking advanced interbody fusion technology for lateral approach lumbar procedures. The company demonstrates regulatory compliance through comprehensive product documentation and patent portfolio.

Lowell Inc. is a precision contract manufacturer specializing in implantable medical devices and components for the orthopedic and medical device industries. The company operates as a B2B manufacturing partner for original equipment manufacturers (OEMs) developing orthopedic implants, spinal devices, and other implantable technologies. Lowell operates multiple CNC machining centers and advanced manufacturing facilities totaling thousands of square feet, employing sophisticated precision machining, laser marking, and finishing technologies. The company has established expertise in high-tolerance component manufacturing, assembly, and quality assurance for regulated medical device applications. Lowell's service offerings include pre-production consultation, design-intent validation, profile tolerancing, GD&T implementation, and critical feature confirmation. The manufacturing process emphasizes data-driven validation, advanced inspection systems with robotic QA capabilities, and high-definition imaging for quality verification. The company serves orthopedic device manufacturers across joint replacement, spinal, and related surgical implant categories. Lowell maintains a quality assurance program aligned with medical device regulatory requirements and demonstrates compliance infrastructure necessary for implantable device manufacturing. The company positions itself as a strategic partner for OEMs navigating regulatory scrutiny, compressed development timelines, and the technical demands of implantable device production.

Artoss, Inc. manufactures NanoBone, a bone graft substitute based on nanotechnology that leverages the body's natural healing capacity. The product features an Amorphous Silica Gel (ASG) matrix that is replaced by autologous organic matrix within 14 days of implantation, creating an osteogenic microenvironment. Clinical data demonstrates healing comparable to autograft with lower complication rates, achieving radiographic and clinical healing within 8 weeks. NanoBone is supplied as a ready-to-use putty with superior handling characteristics, requiring no preparation or mixing. Primary applications include trauma cases, fracture repair, bone defects, and fusion procedures. The product is positioned as a cost-effective alternative to BMP and stem cell-containing products, eliminating the risks and morbidity associated with autograft harvesting. Regulatory pathway and specific FDA clearance status not detailed on site. The company targets orthopedic surgeons and trauma specialists, with clinical validation from peer-reviewed studies and surgeon testimonials.

RevZero, Inc. is a US-based precision medical device contract manufacturer specializing in regulated orthopedic implant manufacturing. Founded in 2007 and headquartered in Chanhassen, Minnesota, the company provides Design for Manufacturability (DFM) guidance, prototype development, and precision production services for medical device engineering teams. RevZero is ISO 13485:2016 certified and FDA-registered, supporting the full product development cycle from early design through production scale-up. The company manufactures complex orthopedic components including plates, screws, spacers, and assemblies for trauma and extremities applications; spinal devices such as interbody spacers, pedicle screws, rods, and fusion systems; and minimally invasive device components. Manufacturing capabilities include multi-axis CNC machining, Swiss turning, wire EDM, precision finishing, and laser marking. The company works with medical-grade materials including titanium, cobalt-chrome, stainless steels, and PEEK. RevZero emphasizes early manufacturing input to prevent late-stage revisions, predictable timelines, full inspection and traceability documentation, and direct engineer-to-engineer communication. The company positions itself as a partner that reduces revision cycles, improves design manufacturability, and delivers parts ready for real-world clinical use.

Twin City EDM & Mfg Inc. is a precision medical device manufacturing partner specializing in complex, tight-tolerance components for the medical, orthopedic, and dental device sectors. Based in Minneapolis, Minnesota, the company offers comprehensive manufacturing capabilities including Swiss CNC turning, CNC milling, wire EDM, sinker EDM, micro hole popping, laser welding, and laser marking. The company holds ISO 9001:2015 and ISO 13485:2016 certifications, supporting medical device development from prototyping through full-scale production. Twin City EDM serves defense, industrial, medical, veterinary, and orthopedic markets, with expertise in specialized materials (titanium, stainless steel, copper tungsten) and advanced metrology-based quality assurance. The firm provides first-article inspections, dedicated engineering support, and expedited quote turnaround for custom precision components.

Primordial Soup is a medical device design and product development consultancy based in Saint Paul, Minnesota. The firm specializes in intelligent product design, uniting engineering and industrial design expertise to develop innovative medical devices and consumer/industrial products. Their medical device portfolio includes orthopedic implant systems (Flow-Nail intramedullary fixation, Flow-Screw bone void filler delivery, DePuy Peak FX hip plate system), respiratory devices (RespirTech InCourage airway clearance therapy system), handheld patient monitoring devices (Nonin Connect Elite pulse oximeter), and autologous fluid concentrator systems (Circle Biologics). Beyond medical, they have designed security systems, vehicle care products, and industrial equipment. The firm serves clients across medical device manufacturers (Boston Scientific, DePuy/J&J, Coloplast, RTI Surgical, Flow-FX, Celling Biosciences), healthcare systems (Mayo Clinic), and non-medical sectors. Primordial Soup offers end-to-end development capabilities including mechanical and electrical engineering, industrial design, and product commercialization support. The firm collaborates with established medical device companies and emerging medtech startups to accelerate development cycles and bring novel solutions to market. No specific regulatory certifications (FDA 510(k), ISO 13485) are mentioned on the website.

Medical Products Resource (MPR) is an orthopedic surgical equipment and instrumentation distributor based in Eagan, Minnesota. The company specializes in surgical positioning systems, leg holders, patient positioners, and orthopedic surgical instruments. MPR manufactures and stocks a comprehensive range of intraoperative positioning devices including leg holders, knee/hip/shoulder positioners, foam inserts, and peg board systems used in orthopedic procedures such as total knee arthroplasty (TKA), hip arthroplasty, and shoulder surgery. The product portfolio includes proprietary systems such as the MPR TKA Alvarado systems, Wishbone Shoulder Holder/Distractor, and lateral hip positioning peg board systems. Beyond positioning equipment, MPR distributes revision instruments, surgical instruments (including the Jobe Shoulder Instrument Set), tourniquet products, spinal products, and bone drills. The company also offers single-use medical/surgical consumables including barrier boots, face shields, carpal tunnel knives, bandages, surgical tape, K-wires, pins, rods, and instrument guards. Additional services include product repair, excess inventory sales, and a preowned division (A-Z Ortho). MPR maintains a physical showroom and operates a hard-to-find products sourcing service. The company serves orthopedic surgical centers, hospitals, and surgical practices across North America with direct sales and customer support.

Advanced Research Medical (ARM) is a US-based medical device manufacturer specializing in spinal surgery instrumentation and implants. The company designs and produces surgical devices for spine procedures, serving surgeons across the United States. ARM's product portfolio includes the OLLIF (Oblique Lateral Lumbar Interbody Fusion) system and the Trident SI (sacroiliac) screw system, both supported by comprehensive surgical technique guides and instructions for use. These devices are designed for orthopedic spinal applications, including lumbar fusion and sacroiliac joint stabilization procedures. The company provides detailed surgical documentation and technical support materials for surgeons implementing these systems in clinical practice.

LockDown Surgical manufactures FDA 510(k)-cleared orthopedic surgical implants specializing in acromioclavicular (AC) joint stabilization and soft tissue repair. The company develops innovative surgical devices for AC joint dislocations, a common shoulder injury in sports and trauma cases. With over 30 years of surgical device development heritage, LockDown provides surgeons with strong, stable, low-profile implant constructs that minimize postoperative complications and enable rapid patient recovery. The LockDown AC Device has become a preferred solution among shoulder, sports, and trauma surgeons, with thousands of successful implantations performed annually across the United States and internationally. The company supports clinical evidence-based practice and provides in-theater surgical support to optimize patient outcomes.

Unity Precision Manufacturing is a medical device and orthopedic implant contract manufacturer based in Osseo, Minnesota, with over 50 years of industry experience. The company specializes in precision machining and assembly of orthopedic implants, surgical instruments, and high-performance medical components. Core capabilities include CNC milling, CNC turning, wire EDM, laser marking, contract assembly, and comprehensive quality inspection services. ISO 9001 & ISO 13485 certified, FDA registered, and GMP compliant, Unity delivers design-for-manufacturing (DFM) support and full traceability through device history records. The company operates state-of-the-art equipment including automated robotic machining centers enabling 24/7 production for high-volume runs, serving both global medtech leaders and emerging startups.

Precera Medical is a contract development and manufacturing organization (CDMO) serving medical device original equipment manufacturers (OEMs). The company specializes in precision manufacturing and engineering solutions for complex medical devices, with particular focus on surgical robotics, minimally invasive surgical systems, endoscopy, spine, motion preservation, and neurostimulation applications. Precera delivers end-to-end capabilities spanning design and process development, rapid prototyping, automation-enabled manufacturing, precision machining (multi-axis and Swiss turning), electrochemical machining, implant and instrument forging, secondary processing, and final assembly. The company emphasizes seamless scaling from prototype to production without risky technology transfers, maintaining quality assurance and regulatory compliance throughout the manufacturing lifecycle. Precera positions itself as a true extension of customer engineering teams, offering robust quality systems, preventive maintenance, new product introduction (NPI) support, and risk management practices. The company serves top-tier MedTech OEMs and is oriented toward supporting advanced, precision-critical device development with validation embedded from inception. No specific FDA, ISO, or CE certifications are explicitly stated on the website, though the quality and compliance messaging suggests regulated manufacturing operations.

Spineology Inc manufactures expandable interbody fusion implants for minimally invasive and ultra-minimally invasive lumbar spine surgery. The company's flagship product line, OptiMesh, comprises conformable, patient-specific expandable interbody devices designed to adapt to individual endplate morphology while delivering through minimal surgical portals. OptiMesh variants support multiple surgical approaches: open TLIF/PLIF, minimally invasive TLIF, and ultra-minimally invasive techniques (OptiLIF and OptiLIF Endo for endoscopic fusion). Recent product launches include OptiMesh Align, which offers up to 20° lordotic range with independent anterior and posterior expansion control, and OptiMesh HA Nano, featuring a nano-thin hydroxyapatite surface treatment designed to promote osseointegration and reduce infection risk. The company's SCOUT IDE (Investigational Device Exemption) trial demonstrated 98% fusion rate at 12 months, 92% patient satisfaction (excellent/good), and clinically meaningful reductions in back pain and disability scores. Spineology reports over 50,000 implants placed and 20+ clinical publications backing product performance. Products incorporate biologics delivery capability and are used in open and percutaneous approaches for lumbar degenerative disc disease, providing disc height restoration, alignment correction, and biomechanical stability. The company serves spine surgeons and neurosurgeons in hospital and surgical center settings across the United States.