Orthopedic Implants in Colorado

Paragon 28 is a wholly owned subsidiary of Zimmer Biomet Holdings, Inc., specializing in foot and ankle surgical solutions. Founded in 2010, the company develops innovative implants, fixation systems, and biologics for treating complex foot and ankle pathologies, including trauma, bunions (hallux abducus valgus/HAV), ankle fusions, and hindfoot conditions. Primary product lines include the Phantom® intramedullary nail systems, Silverback™ ankle fusion plating systems, Gorilla® plating systems (LisFranc, Pilon, Lapidus), PRECISION® minimally invasive bunion systems, and APEX 3D™ total ankle replacement with laser-guided technology. The company offers biologic solutions including BEAST™ demineralized bone matrix, MGNUM™ bone void fillers, and PARADERM™ dermal matrices. Paragon 28 also provides SMART 28℠ advanced pre-operative planning technology and patient-specific surgical solutions. The company serves foot and ankle surgeons, podiatrists, and orthopedic specialists across North America and internationally. Paragon 28 operates manufacturing and distribution from its Colorado headquarters, with a sales office in Michigan and international presence in Ireland. The company emphasizes surgeon-driven innovation, evidence-based design, and cost-effective solutions for challenging foot and ankle cases.

ToughWare Prosthetics manufactures affordable, durable prosthetic devices for upper-limb amputees, specializing in hand and arm prosthetics designed for everyday functional use. The company produces transradial and modular prosthetic systems engineered with polymer resins and state-of-the-art manufacturing processes. Product lines include the patented Equilux™ VO/VC terminal device, Vari-Pinch Prehensor™ (V2P™), Retro Classic Hook™, International Transradial Adjustable Limb™ (ITAL™), Ventilated Transradial Sport Socket™ (VTSS), and field-serviceable Modular Cable System (MCS) components. ToughWare's design philosophy emphasizes battery-free, low-maintenance, waterproof functionality suitable for work, recreation, and daily living—positioning products as practical alternatives to expensive electronic prosthetics. Devices are quick-fit (requiring only basic tools, no casting) and marketed for durability and affordability across diverse global markets, including economically constrained populations. All products are designed, developed, tested, and manufactured in the United States. The company targets amputees seeking robust, cost-effective prosthetic solutions for activities ranging from home repair to sports.

Cerapedics is a biopharmaceutical company specializing in peptide-enhanced bone graft materials for spinal fusion surgery. The company develops and markets bone growth accelerators (BGAs) designed to improve fusion rates and reduce time to fusion in orthopedic procedures, particularly in the lumbar and cervical spine. Their primary product portfolio includes PearlMatrix™ P-15 Peptide Enhanced Bone Graft, recently FDA-approved as the first bone growth accelerator indicated to accelerate fusion in lumbar spine (single-level TLIF), and i-FACTOR® P-15 Peptide Enhanced Bone Graft, an established product approved for anterior cervical discectomy and fusion (ACDF) in use since 2015. Both products incorporate P-15 peptide technology to enhance osteogenic activity and bone formation. Cerapedics emphasizes rigorous clinical evidence and patient outcomes in their marketing and regulatory approach. The company maintains regulatory compliance with FDA approval for spinal fusion applications and conducts clinical trials to demonstrate superiority versus standard autograft solutions. Manufacturing and distribution capabilities support surgeon access across spine surgery centers and hospitals. The company serves orthopedic surgeons, spine specialists, and hospital networks focused on improving fusion outcomes and reducing operative time.

3D-Side is a software and patient-specific medical device company specializing in AI-powered 3D preoperative planning and personalized healthcare solutions. The company operates a cloud-based platform called Customize, which integrates case management, communication, quality management, and full traceability for patient-specific medical device production. The platform supports three main product lines: 3D-Arthro (arthroplasty planning and patient-specific instrumentation for shoulder and ankle, with FDA 510(k) clearance), 3D-Cut (bone tumor resection and corrective osteotomy cutting guides), and 3D-Skull (cranioplasty solutions with AI-based segmentation and custom cranial implant design). 3D-Side targets neurosurgeons, orthopedic surgeons, arthroplasty implant manufacturers, and patient-specific device manufacturers. The platform covers the entire surgical journey from preoperative planning through intraoperative execution to postoperative surveillance. The Customize platform features AI automation for segmentation, communication, document generation, and case management, enabling scalable production of patient-specific devices. The company designs turnkey solutions tailored to customer implant philosophy and surgical approach, with rapid design and manufacturing capabilities. 3D-Skull specializes in cranioplasty molds for intraoperative PMMA implant creation, reducing lead times and manufacturing costs.

AlloSource is a human tissue allografting company founded in 1994, specializing in enhanced tissue products for orthopedic and surgical applications. The company processes and preserves donor tissue to create allografts for bone, cartilage, and soft tissue repair. Primary product lines include AlloMend (soft tissue grafts), AlloFuse Select (bone grafting solutions), and AceConnex (cartilage solutions). AlloSource serves orthopedic surgeons, sports medicine specialists, and spinal surgery markets. The company's products enable surgeons to perform minimally invasive procedures with reduced incision sites compared to autografting approaches. AlloSource operates tissue processing and preservation facilities and coordinates with donor networks through partnerships such as Donor Alliance. The company markets its solutions at conferences including the International Sports Medicine Fellows Conference (ISMF), indicating strong engagement with sports medicine and orthopedic surgery communities. Operations include master tissue processing technicians trained in advanced graft preparation and preservation. Allografts are distributed for ACL reconstruction, dental implant support, spinal fusion, and other orthopedic repair applications. The company emphasizes the donor legacy program and patient success stories to support clinical adoption and patient awareness.

Promethean Restorative is a medical device manufacturer specializing in sacroiliac (SI) joint stabilization and fusion solutions. The company's flagship product is the DYNAMIS™ Implant System, a complete procedural solution for SI joint fusion featuring a 3D-printed titanium implant with advanced instrumentation. The DYNAMIS™ system incorporates patent-pending thread design technology engineered to provide true compression of the ilium and sacrum, maximizing fusion opportunity. Key features include DYNABridge (titanium lattice scaffold structure for bone bridging), DYNAVex (negative bead porosity increasing surface area approximately 2X for enhanced bone integration), DYNABite (self-drilling/self-tapping tip for simplified insertion), DYNATorx (approximately 30% greater insertional torque than traditional drivers), and DYNA-X (multiple insertion and revision capability). The implant system is designed for orthopedic spine surgeons, neurosurgeons, and pain management specialists performing sacroiliac joint treatments. Promethean Restorative targets practitioners treating SI joint conditions, distributors serving geographic markets, and patients seeking pain relief from spinal conditions. The company provides comprehensive instructional materials including surgical technique guides and product brochures. Manufacturing capabilities include 3D printing of titanium implants and precision instrumentation. The company emphasizes innovation in first-to-market spinal solutions with focus on surgical ease-of-use and long-term patient outcomes.

Synergy Spine Solutions is a medical device company founded in 2005 by surgeons and based in Louisville, Colorado. The company specializes in artificial cervical disc replacement technology for treating degenerative disc disease. The flagship product, the Synergy Disc®, is an FDA-approved cervical arthroplasty device featuring a built-in 6-degree lordotic core designed to preserve motion while improving sagittal alignment—the first and only artificial cervical disc engineered specifically for alignment improvement combined with intentional motion preservation. The device is manufactured from time-tested, nickel-free materials and provides an alternative to traditional cervical fusion surgery. Currently available in the United States, Europe, Australia, Canada, South Africa, and Malaysia, the Synergy Disc leverages over 20 years of orthopedic medical device design and development expertise. The company is led by CEO Josh Butters and Chief Medical Officer Dr. Neil Duggal, with a focus on advancing spine surgery outcomes and expanding global clinical adoption through ongoing case studies and surgeon partnerships.

Highridge Medical is a global medical device company specializing in innovative spinal solutions and motion preservation technologies. Established in 2024 following H.I.G. Capital's acquisition of the Spine and EBI businesses from ZimVie, the company develops comprehensive spine surgical portfolios including cervical and lumbar disc replacement systems, deformity fixation platforms, interbody fusion devices, and vertebral body tethering systems. Highridge's product line features the Mobi-C® Cervical Disc, the upcoming activL® Lumbar Disc (launching July 2025), the Vital™ Navigation System for open and minimally invasive procedures, and additional fixation and fusion solutions. The company emphasizes surgeon-driven design, clinical research and development, and medical education to advance spine care outcomes. Leadership includes Executive Chairman Eric Major and CEO Rebecca Whitney, with a commitment to advancing patient mobility and strength through accountable, compassionate partnerships with healthcare providers.