Orthopedic Implants in California

Top Shelf Manufacturing, LLC (operating as Top Shelf Orthopedics) is a manufacturer of orthopedic bracing, support systems, and cold therapy devices serving healthcare professionals and patients for over two decades. The company manufactures a comprehensive range of orthopedic solutions including functional knee braces, post-operative bracing, shoulder immobilizers and abduction systems, ankle braces, foot and ankle support products (boot walkers, post-op shoes), hand and wrist supports, elbow braces, spine and cervical products, hip supports, and cold therapy systems. Featured products include the Sierra Cold Therapy System with customizable temperature and time settings. The product portfolio also encompasses surgical positioners, home therapy kits, ambulatory aids, and biologics (Gold Rush PRP). All products carry limited warranties ranging from 6–12 months depending on product family. The company processes orders on net-30 terms and ships via UPS ground with 24-hour turnaround for orders received before 2:00 PM Pacific time. Manufacturing and customer service operations are based in Tracy, California. Top Shelf targets orthopedic practices, hospitals, clinics, and direct-to-consumer markets including athletes, post-operative patients, and individuals managing chronic joint conditions.

Berkeley Biologics is a tissue bank and contract manufacturer specializing in human allograft implants for orthopedics, spine, sports medicine, trauma, dental, and wound care. The company has 35+ years of expertise in tissue processing and transplantation. Core product lines include D-FIBER (demineralized cortical fiber matrix for bone regeneration), AcelloDerm (pre-hydrated acellular dermal matrix), AltiPly (lyophilized placental membrane for wound care), InteguPly (acellular dermis for sports medicine and wound repair), and TranZgraft (processed allograft tissues including tendons and ligaments for sports medicine). All products undergo rigorous donor screening, communicable disease testing, and quality assurance per AATB and FDA standards. Berkeley Biologics processes tissues using proprietary methods including low-dose e-beam irradiation and gamma sterilization to achieve sterility assurance level (SAL) of 10-6, while preserving native matrix structure, collagen integrity, and endogenous growth factors (BMP, FGF, IGF-1, PDGF, TGF-β). The company operates state-of-the-art manufacturing facilities in Northern California and offers turnkey contract manufacturing, private-label allograft opportunities, custom implant development, engineering and validation support, and inventory management services. Regulatory compliance includes FDA registration (21 CFR Parts 820 and 1271), AATB accreditation, and tissue bank licensure in California, Florida, Maryland, New York, Delaware, Illinois, Oregon, and Canada (CTO registration). The company serves surgeons, hospitals, and surgical centers across multiple specialties.

Biowy Corporation is a medical device manufacturer headquartered in Lake Forest, California, producing a diversified portfolio of disposable medical devices and biologics. The company manufactures cord blood processing and preservation kits for stem cell banking and regenerative medicine applications, tympanostomy tubes for otologic procedures, percutaneous central catheter (PICC) systems in multiple lumen configurations, midline catheters for vascular access, vascular access ports for long-term infusion therapy, demineralized bone matrix (DBM) products including C-Mix formulations for orthopedic and spinal applications, and hyaluronic acid products. Biowy operates both corporate headquarters and a dedicated manufacturing facility in Lake Forest. The company serves hospitals, surgical centers, otolaryngology and pediatric practices, and healthcare systems requiring single-use sterile medical devices. Products emphasize biocompatible materials, sterile construction, and clinical safety. The company maintains customer service operations with standard business hours Monday–Friday, 8am–5pm PST, and accepts inquiries through multiple channels including email, phone, and web-based contact forms.

Hand Biomechanics Lab, Inc. designs, manufactures, and distributes innovative orthopedic surgical devices specializing in hand and wrist trauma management and rehabilitation. The company develops proprietary device concepts through research-driven innovation, cadaver testing, and FDA clearance processes, followed by in-house assembly and quality control. Their product portfolio includes external fixation systems for complex hand and wrist fractures, as well as therapeutic devices for post-operative joint contracture management. Primary product lines include the Digit Widget (for severe PIP flexion contracture reversal), WristJack External Fixation System (distal radius fracture treatment with adjustable palmar tilt and radial inclination), PIP Fix (external fixator for PIP joint dorsal fracture dislocations), and ECTR Blade Assembly (endoscopic carpal tunnel release compatible with 3M and MicroAire systems). The company manufactures sterile, packaged devices delivered directly to surgical facilities. Hand Biomechanics Lab serves hand surgeons, orthopedic surgeons, and surgical centers. The organization operates with a patient-centric clinical approach and demonstrates commitment to FDA regulatory compliance and quality manufacturing standards.

Universal Punch Corporation is a leading contract manufacturer and design partner for orthopedic and dental medical device companies worldwide. Specializing in self-retaining screw instruments, medical gages, and precision tooling, Universal provides comprehensive product development, advanced CNC machining, instrument and gage manufacturing, laser etching, and surface treatment services. The company manufactures a broad range of medical components including titanium screws, screw blanks, drills, reamers, bur blanks, finished burs, forge caps, and customer handles. Beyond medical, Universal is an established industrial tooling supplier offering punches (knockout, quill, ejector, recess), carbide dies, reamers, high-speed steel tools, and specialized gaging fixtures and fastener gages. The company supports cold heading applications and provides quality system resources and product development expertise to complement customers' internal capabilities. With a full-service manufacturing approach and worldwide sales support, Universal serves the orthopedic, dental, and industrial fastener markets.

SI-BONE, Inc. is a medical device manufacturer specializing in sacroiliac (SI) joint fusion systems. The company develops and markets the iFuse Implant System, a minimally invasive sacroiliac joint fusion implant designed to stabilize and fuse the SI joint for patients with chronic SI joint pain and dysfunction. The iFuse Implant, available since 2009, is a small, triangle-shaped implant used in minimally invasive surgical procedures. SI joint dysfunction accounts for 15–30% of chronic low back pain cases in the patient population. SI-BONE provides comprehensive patient education, diagnostic resources, and physician training to support diagnosis and treatment of SI joint-related pathology. The company maintains an active network of trained surgeons and offers patient events, webinars, and educational materials to help patients understand SI joint anatomy, dysfunction, and treatment options including the iFuse procedure. SI-BONE serves orthopedic surgeons, spine specialists, and patients across the United States and internationally.

OrthAlign, Inc manufactures surgical navigation and alignment technology for orthopedic joint replacement procedures. The company's primary product platform is Lantern®, a handheld navigation system designed to improve precision and efficiency in total hip arthroplasty (THA), total knee arthroplasty (TKA), revision knee procedures, and partial knee arthroplasty (PKA). Lantern Hip and Lantern Knee are modular product lines that enable surgeons to perform joint replacements with enhanced accuracy in various surgical settings, including ambulatory surgery centers (ASCs), hospital operating rooms, and outpatient facilities. The technology is characterized as simple and efficient, designed to work with any surgeon and any OR setup without requiring specialized infrastructure. OrthAlign positions its offerings for the growing outpatient joint replacement market, emphasizing accessibility and ease of adoption across diverse surgical environments. The company maintains a surgeon finder tool to help patients locate practitioners using OrthAlign technology. While specific regulatory certifications are not detailed in the available content, orthopedic surgical navigation systems typically require FDA 510(k) clearance for US distribution. The company's focus on ASC compatibility and surgeon accessibility suggests a market strategy targeting both high-volume academic centers and emerging outpatient surgical venues.

Rhausler, Inc. is a medical device manufacturer specializing in cervical spine surgery solutions. The company designs and produces innovative anterior cervical fusion and fixation systems for levels C3 through C7, addressing the surgical complexity of treating elderly patients with degenerative spinal disorders. Their product portfolio includes the Rhausler Dynamic Cervical Plate System, featuring a low-profile, trapezoidal design that conforms to patient anatomy with stackable, articulating capabilities for multi-level constructs, and the Rhausler PLAGE™ Anterior Cervical Fusion System, a one-piece integrated plate/cage design requiring minimal fixation (2 screws) with roughened titanium surfaces for direct vertebral endplate purchase and enhanced bone graft integration. Products are designed by spine surgeons with over 15 years of market presence and more than 5,000 documented patient cases demonstrating consistent outcomes. Rhausler positions itself as an alternative to commoditized cervical implant solutions, offering differentiated surgical instruments that reduce postoperative complication risk in complex elderly patient populations. The company recently announced a direct replacement for Aesculap cervical spine implants, expanding clinical options for surgeons transitioning from competing systems.

Kyocera Medical Technologies manufactures high-quality orthopedic implants and devices for joint and spine surgery. The company specializes in orthopedic solutions that combine advanced materials and innovative engineering to enhance surgical outcomes and patient longevity. Product lines include joint reconstruction and spine implant systems designed to address diverse patient anatomies and surgical demands. Kyocera Medical leverages the parent company's long-standing legacy of quality and precision manufacturing. The company operates manufacturing and engineering facilities, with headquarters in Redlands, California and an R&D center in Austin, Texas. Kyocera Medical distributes products through an established network of medical device distributors. The company is committed to regulatory compliance and clinical excellence in orthopedic surgery.

CG MedTech USA, Inc. (Irvine, California) is a specialized manufacturer of orthopedic and spinal implant technologies serving Ambulatory Surgery Centers (ASCs), hospitals, and surgical specialists. The company offers a comprehensive portfolio spanning spinal implants, trauma fixation systems, sports medicine devices, pain management solutions, and biologic products. With a commitment to value-based pricing, CG MedTech provides competitively priced, quality-assured implants that challenge market premiums while maintaining rigorous R&D investment and industry compliance. The company serves manufacturers, distributors, surgeons, hospitals, and patients with a focus on clinical outcomes and procurement efficiency. Global operations include headquarters in South Korea and dedicated U.S. sales and R&D centers, positioning CG MedTech as a reliable partner for cost-effective orthopedic solutions without compromising device quality or performance.

TiMed manufactures a complete line of modular prosthetic components fabricated from titanium, stainless steel, and aluminum using state-of-the-art manufacturing processes. Product portfolio includes titanium components, aluminum components, stainless steel components, pediatric components (22mm and 25mm systems), extra heavy-duty components, knee modules, prosthetic feet, pylons, BK kits, and additional specialized prosthetic parts. The company serves certified prosthetists and orthotists (CPOs/LPOs) as well as prosthetic device manufacturers and clinics. Products are CE marked and tested to meet ISO 10328 standard for durability and safety. Titanium prosthetic components carry a 24-month warranty; XFA, JRS, and Sach Foot components come with 36-month warranty. TiMed operates as a B2B component supplier with a distribution network and provides prosthetic build flowcharts and technical guidance for prosthetic design and assembly. The company emphasizes custom design capabilities, including non-conventional applications and high-weight-capacity components (100–500 lbs). Known for prompt delivery and continuous quality improvement.

Xenco Medical is a San Diego-based medical device manufacturer specializing in single-use, composite polymer spinal implant systems. The company manufactures the SETx Technology platform, which includes cervical interbody systems (ACDF), lumbar interbody systems (ALIF, PLIF, TLIF), pedicle screw systems, and cervical plate systems. Additional products include Sorrento Bone Substitute, CancelleX porous titanium implants, TrabeculeX Continuum, and HoloMedX (a holographic surgical visualization system). Xenco's core innovation is the development of pre-assembled, sterile, single-use surgical instruments and implants manufactured from highly reinforced composite polymer with exceptional durability and interfacial bond strength. This approach eliminates traditional reprocessing, autoclave sterilization, inventory management delays, and cross-contamination risks associated with reused metal instruments. Each surgical system is disposable after a single use, ensuring peak condition performance and consistent calibration. The company targets orthopedic surgeons and surgical centers seeking to improve operating room efficiency, reduce infection risk, and optimize patient outcomes. Xenco has received multiple innovation awards, including Fast Company's World's Most Innovative Companies (2023, 2025) and Innovation by Design Award (2024). The company maintains field operations across the United States with regional biomedical and inventory management personnel.

Elevation Spine is a medical device manufacturer specializing in advanced spinal fusion implants and integrated-fixation systems. Founded in 2015 and based in Monterey, California, the company develops proprietary Saber Technology for anterior cervical fusion procedures. The flagship Saber-C system is a modular cervical fusion platform featuring a zero-profile anterior cervical plate, titanium interbody spacers, and flexible fixation options (inline spikes or screws). The system is designed to enable less invasive surgical approaches with minimized exposure, reduced procedural steps, and improved surgeon efficiency. Saber-C accommodates fixation versatility and accommodates adjacent segment fusion scenarios. The company focuses exclusively on spinal implants and fusion technologies to improve surgical outcomes and procedural simplification.

Spinal Elements is a Carlsbad-based medical device company founded in 2004 that develops innovative, proprietary spine surgery technologies for minimally invasive procedures. The company specializes in advanced interbody solutions, metal-free fixation devices, and biologics for TLIF (transforaminal lumbar interbody fusion), ALIF (anterior lumbar interbody fusion), and posterior fixation applications. Their product portfolio includes the Ventana interbody system (available in lumbar and cervical configurations with 3D-printed options), the Luna TLIF portfolio, the Karma metal-free fixation system, the Sapphire X cervical plate system, and comprehensive core and biologics solutions. Spinal Elements operates as a market leader in commercializing spine surgery solutions through proprietary technologies, strategic distributor relationships, and surgeon partnerships. The company manufactures devices for hospital and ambulatory surgery center environments. Multiple products have received FDA 510(k) clearance, including recent clearances for the Ventana ALIF System and Sapphire X expansions. Spinal Elements has achieved notable contracts including a Vizient Innovative Technology Contract for the Karma Fixation System, demonstrating acceptance within major healthcare provider networks. The company maintains a surgeon-centric approach, collaborating with clinical experts to develop patient-first procedural solutions addressing the fastest-growing segments of the spine surgery market.

Molecular Matrix, Inc. is a biotechnology and biomedical engineering company founded in 2011, headquartered in Rancho Cordova, California, specializing in next-generation osteobiologic technologies and bone regeneration solutions. The company's flagship product, Osteo-P® BGS (bone graft substitute), is a hyper-crosslinked carbohydrate polymer that received FDA 510(k) clearance in 2017. Osteo-P® BGS is designed to address critical challenges in orthopedic reconstruction, spine surgery, and trauma care by providing an osteoconductive synthetic scaffold that mimics the physiologic microenvironment for bone growth and repair. The product features superior porosity (75–95%) with optimal pore size (200–500 µm), is radiolucent for real-time radiographic visualization, and features a controlled degradation profile that matches new bone formation. As a synthetic, non-immunogenic, disease-transmission-free scaffold, Osteo-P® BGS offers surgeons a ready-to-use, reliable alternative to allograft and autograft materials. Under the leadership of CEO Charles Lee, Ph.D., Molecular Matrix develops therapeutics inspired by embryonic development and physiologic principles to accelerate healing, promote faster recovery, and enhance patient safety in musculoskeletal repair. The company serves orthopedic, spine, and trauma markets, positioning its osteobiologic platform for fracture repair, reconstruction, and degenerative tissue applications.

Dentis USA Corporation is a global manufacturer of comprehensive dental and medical solutions, founded in 2005 and operating in over 80 countries. The company specializes in dental implants and implant systems, including the emerging AXEL line and SQ mini implant technologies. Beyond implantology, Dentis offers integrated solutions across digital dentistry (CAD/CAM, guided implant surgery systems, 3D printing), equipment and clinic solutions (surgical kits, dental units, surgical lighting), and advanced biomaterials for enhanced clinical outcomes. The company operates three strategic divisions: Dentis (core dental/medical solutions), Luvis (clinical and surgical solutions), and Global Dental Implant Academy (GDIA), an established surgical training provider offering live patient implant training and professional education. Dentis serves dental professionals, clinics, and hospitals with a focus on innovation, clinical evidence, and practitioner development.

Meduloc LLC is an orthopedic medical device company founded in 2016 by orthopedic hand surgeons and Cor Medical Ventures. The company develops and manufactures minimally invasive, intramedullary implants designed to provide stable fixation and secure reduction for small and long-bone fractures. Meduloc's product platform addresses clinical needs in internal fixation of small long bones using intramedullary fixation technology. The company operates through a partnership model with Cor Medical Ventures, a contract development and manufacturing firm that provides engineering, prototyping, testing, quality assurance, regulatory compliance, clinical support, and commercialization services including contract manufacturing and distribution. The company is advised by a surgeon advisory board of leading orthopedic specialists including hand surgeons and trauma surgeons from major academic medical centers. Leadership includes Sarah Sachinis (CEO/President), Michael Collins (Director/COO), Benjamin Arnold (Director/Co-Founder, CEO of Cor Medical Ventures), and Brian Bowman (Co-Founder, CTO of Cor Medical Ventures). Meduloc targets surgeons and surgical centers performing small and long-bone fracture repairs, with particular expertise in hand and upper extremity trauma and orthopedic reconstruction.

Aesclepius Corporation is an early-stage medical device company specializing in next-generation orthopedic implants and surgical tools for joint repair. The company develops innovative surgical instrument systems focused on foot and ankle procedures, including plantar plate repair solutions. Their product portfolio features patented surgical technologies such as specialized clamps, cinching devices, and drill guides designed to enable surgeons to achieve optimal patient outcomes through efficient, effective, and reliable instrumentation. The company is committed to advancing orthopedic surgical capabilities through proprietary technology and precision-engineered surgical repair systems.

Newton Implant Systems manufactures innovative dental implant systems and surgical instruments for implant dentistry. The company's flagship product is the Ni2 (Newton 2) implant system, designed by Dr. Samuel Lee, featuring a patented simplified 2-step drill protocol that reduces surgical time and complexity. The system enables immediate loading of implants using a single-drill approach. Newton Implant Systems operates a dental laboratory based in Southern California providing restoration services and custom abutments as part of its integrated implant solution. Product offerings include dental implants, premilled abutments, scan bodies, digital bases, surgical instrument kits (MIT Gold Instrument Kit, 3-In-1 Kit, Fixture Remover Kit, Ultimate Crestal & Lateral Sinus Lift Kit), bone grafting materials (MIT-OS Bonegraft), membranes (TI-Enforced EPTFE Membrane MIT-Screen), suturing materials (Chromic Catgut 5-0), and screw-retained crown restorations with titanium bases. The company serves general dentists and implant specialists seeking simplified implant protocols and comprehensive restoration solutions. Newton Implant Systems offers continuing education courses and maintains detailed instructions for use (IFU) documentation. The company provides B2B B2C e-commerce ordering through its WooCommerce platform with tiered pricing for registered practitioners.

Evolve Manufacturing Technologies Inc. is a contract manufacturer of complex medical devices and life sciences instruments, operating a 75,000 sq ft facility in Fremont, California. The company specializes in end-to-end manufacturing services for original equipment manufacturers (OEMs) across multiple medical specialties including surgical robotics, capital medical devices, disposable surgical tools, and life sciences biotech applications. Their service portfolio encompasses design-to-manufacturing support, full production runs, repairs and spares management, and quality-assured supply chain solutions. Evolve holds ISO 13485:2016 and ISO 9001:2015 certifications, demonstrating compliance with medical device quality management standards. The facility includes ISO 14644-certified cleanrooms (ISO 7 and ISO 8 classifications), essential for sterile device and precision component manufacturing. The company serves Fortune 500 OEMs and established medtech innovators across surgical robotics, ultrasound imaging, spinal implants, and semiconductor robotics sectors. Evolve positions itself as a collaborative partner rather than transactional supplier, offering flexibility in production scaling, component sourcing, and logistics support. The company is woman-owned and has received industry recognition including the 2025 Global Technology Award for Best Woman-Owned Contract Manufacturer.

Shalby Advanced Technologies (SAT), formerly Consensus Orthopedics and originally Hayes Medical (founded 1992), designs, develops, and manufactures orthopedic joint implants in the United States. The company specializes in knee and hip replacement systems, with over 32 years of manufacturing heritage and zero product recalls across more than 120,000 implantations. SAT operates a vertically integrated, FDA-approved US manufacturing facility in El Dorado Hills, California, encompassing R&D, design, quality control, sterilization, and packaging. Current product portfolio includes total and unicondylar knee systems (Consensus® Knee System [CKS], Tahoe Unicondylar Knee System [TUKS], Revision Knee System [RKS]) and hip systems (Consensus® Hip System [CHS], Taperset™, Unisyn™, Bipolar systems, and CS2™ cups). TUKS, the company's flagship innovation, features minimal bone resection instrumentation and natural soft tissue restoration design. SAT distributes globally through partnerships with healthcare distributors and serves surgeons, hospitals, and patients worldwide. The company emphasizes quality standards, regulatory compliance, and patient care outcomes as core differentiators in the orthopedic implant market.

TopMed Medical Devices Inc manufactures high-performance surgical power tools and spinal fixation systems for orthopedic, spine, and neurosurgical procedures. The company develops ergonomic, precision-engineered instruments designed to enhance surgeon control and procedural outcomes. Product portfolio includes five surgical power system platforms: System 3400 (lightweight pen-style tool for orthopedic, neuro, and ENT procedures), System 3400-IV (enhanced variant), System 3500 (small bone micro power system for podiatric and foot/ankle surgery), System 5800 (TM5800 Orthomax drill and reaming system for orthopedic applications), and System 6600 (multi-functional surgical power tool with lithium battery power). All systems feature comprehensive accessory and kit compatibility. Spinal implant offerings include the RS8 LEGEND Spinal Fixation System (general posterior approach spinal fixation), RS8 LONG Posterior Spinal Fixation System (minimally invasive, high-efficiency design), NEST Interbody System (hollow rectangular lumbar implant with solid and porous structures for bone in-growth), and NEST-C Interbody System. TopMed emphasizes surgical precision, safety, and ergonomic design. The company actively recruits independent spine representatives for select US territories, indicating established distribution infrastructure. Clinical applications span orthopedic, spine, neurosurgical, and podiatric specialties. Manufacturing capabilities include power system development and implant fabrication.

SAIL Fusion is a medical device company specializing in sacroiliac (SI) joint fusion systems. The company manufactures the BowTie SI Fusion System, a novel implant designed to treat sacroiliac joint disorders using principles established by the AO Foundation. The BowTie implant features a distinctive double-dovetail geometry that maximizes rigidity and resistance to motion in all planes, addressing a recognized clinical need among spine surgeons. SAIL Fusion's approach applies validated fusion principles—minimal tissue disruption, thorough joint preparation, and rigid fixation—traditionally used in other joint fusions (ankle, etc.) to sacroiliac fusion. The company targets orthopedic and spine surgeons and surgical centers performing SI joint fusion procedures. Product development reflects surgeon feedback from surveys indicating demand for improved sacroiliac fusion solutions. The BowTie system is designed for percutaneous or minimally invasive implantation to achieve stable arthrodesis of the SI joint.

KB Dental Products is a dental supply distributor and wholesale supplier offering a comprehensive range of dental implant systems, regenerative materials, surgical instruments, and endodontic products. Product lines include implant overdenture systems, multi-unit implant prosthetics, Hiossen-compatible prosthetic components, guided bone regeneration (GBR) materials, implant surgical instruments, endodontic root canal sealers and fillers, and implant motors with piezoelectric technology. The company operates a B2B wholesale model, positioning itself as a growth partner for dental retailers and practitioners by providing high-quality, competitively priced products to support profitability in the competitive dental retail market. The company maintains an e-commerce platform for dealer and distributor ordering and actively recruits wholesale partners through a formal dealer inquiry program. Product offerings span implant placement, bone augmentation, prosthetic restoration, and endodontic specialty care, serving general practices, implant specialists, and dental laboratory professionals.

Tenon Medical, Inc. designs and manufactures sacroiliac (SI) joint fusion implants and surgical systems for minimally invasive orthopedic procedures. The company's flagship product is the Catamaran® SI Joint Fusion System, a single-implant, titanium-based solution that uses an inferior-posterior surgical approach to fuse the sacroiliac joint. The system features a patented osteotome bridge design with fenestrated pontoons that transfix the ilium and sacrum along the longitudinal axis, facilitating bony in-growth and arthrodesis while maintaining a surgical trajectory away from critical neural and vascular structures. Clinical data from the prospective, multi-center MAINSAIL Study (published 2024) demonstrated 80% success rate at 6 months, with 61.6% pain reduction (VAS), 43% functional improvement (ODI), and 93.3% patient satisfaction. No serious device-related adverse events, reoperations, or reinterventions were reported. The system is indicated for sacroiliac joint fusion in cases of SI joint disruption and degenerative sacroiliitis. Tenon Medical provides comprehensive surgical documentation including Instructions for Use (IFU), Surgical Technique Manuals, and biomechanical testing data. The company also offers the SImmetry SI joint fusion system. Customer service and training support available via dedicated hotline.

DIO USA Corporation is a dental implant manufacturer and digital surgical solutions provider operating globally with presence in over 70 countries. The company specializes in dental implant systems featuring proprietary dual surface treatment technology (hybrid surface treatment and UV activation technology) designed to enhance osseointegration and clinical outcomes. Core product lines include the DIO Implant System with surgical kits, DIO NAVI (a fully digital flapless guided surgery system), DIO NAVI Full Arch for immediate full-arch implant placement, and DIO Ortho NAVI for orthodontic applications. The company offers comprehensive equipment and materials for implant dentistry. DIO's clinical solutions span immediate implant placement, general implant prosthetics (cemented restorations), guided surgical procedures, and advanced surface treatments. The DIO NAVI Full Arch system has achieved over 17,000 cases worldwide and 8,256 global cases documented. DIO maintains a robust global network with headquarters, overseas subsidiaries, and distributors across 33 countries. The company provides practitioner education through monthly and regional seminars, technical support, product catalogs, clinical guides, and educational materials. Manufacturing and regulatory credentials align with international dental implant standards. DIO has received export recognition including a 50 Million Dollar Export Tower award, indicating significant international market penetration and established regulatory compliance across multiple jurisdictions.

Carlsmed is a publicly traded medical technology company specializing in AI-enabled personalized spine surgery solutions. The company's flagship aprevo® platform integrates artificial intelligence and 3D printing technology to design custom titanium spinal implants and deliver detailed, patient-specific surgical plans. The platform includes 3D surgical planning and visualization (myaprevo®), personalized procedural protocols, and biomechanically optimized implants designed to promote fusion. FDA-cleared for lumbar and cervical spinal fusion procedures, Carlsmed has completed over 50 cases. The company targets the substantial U.S. market opportunity of approximately 445,000 annual lumbar spine fusion procedures. With strong clinical evidence foundation and ISO 13485 certification, Carlsmed is expanding internationally following its July 2025 IPO.

KevinRoot Medical is a precision orthotic manufacturing and clinical technology company founded in 1959 by Dr. Merton Root, who pioneered the functional orthotic approach to biomechanical treatment. The company manufactures custom foot orthoses and ankle-foot orthoses (AFOs) based on 3D volumetric scanning technology via its FootID Pro platform, which captures detailed foot geometry for patient-specific device fabrication. KevinRoot Medical offers eight custom foot orthosis configurations (Root, Active, Dress, Therapeutic, UCBL, Military, Sport Specific, and Pathology) designed for biomechanical control, pressure redistribution, and performance support. The company also manufactures brace systems including the Turbomed XTERN dynamic AFO, Richie Brace for posterior tibial tendon dysfunction (PTTD) and ankle instability, Gauntlet Brace for severe deformity, and Traditional AFO designs. With over 845 modification options per device, KevinRoot Medical delivers highly customized orthotics with 24-hour rapid turnaround. The company serves podiatrists, physical therapists, orthopedic surgeons, athletic organizations (including the LA Lakers and Chicago Marathon medical team), and military personnel. Clinical decision-support tools help providers match orthotic designs to biomechanical control needs, pressure redistribution requirements, and performance demands. KevinRoot Medical operates within a broader ecosystem including FootID Pro (prescription platform), LearnBIQ (biomechanics education), WalkLab (movement health brand), and GoMFO (clinician-recommended orthotics retail).

Alliage is a global dental and medical equipment manufacturer with 80 years of industry experience, operating across more than 50 countries through six primary brands: Dabi Atlante, Saevo, D700, Medens, Denimed, and Prexion. The company specializes in dental chairs, imaging systems, handpieces, implants, and bio-materials for professional dental and medical practitioners. Manufacturing capabilities include advanced automation with laser cutting, welding robots, and automated painting, with vertical integration allowing the company to manufacture over 80% of component parts in-house. Production facilities are located in Ribeirão Preto, Brazil and Córdoba, Argentina, with approximately 600 employees globally. The company produces approximately 25,000 dental sets annually and maintains 537 points of sale and technical service units worldwide. Distribution includes 9 sales offices in Brazil, plus offices in Mexico, Argentina, Dubai, and the United States. Dabi Atlante represents the company's heritage brand emphasizing tradition and quality in dentistry; Saevo focuses on innovative solutions; D700 targets cost-effective clinical solutions; Medens produces implants and bio-materials; Denimed is the Argentine subsidiary with 41 years of history; and Prexion represents recent Brazilian expansion. The company emphasizes sustainable manufacturing practices, quality assurance, and verticalized production with comprehensive testing and validation protocols.

Aurora Spine & Pain is a medical device company founded in 2012 that develops less invasive implants for spinal and sacroiliac (SI) joint conditions. The company specializes in minimally invasive spine solutions spanning the cervical, thoracic, lumbar, and SI joint regions. Their product portfolio addresses patients with degenerative disc disease, spinal stenosis, and SI joint dysfunction through implant-based interventions. Aurora emphasizes high-quality device design with a focus on patient outcomes and reducing surgical complexity. The company maintains an active clinical research program, including published 12-month fusion outcome data in peer-reviewed journals. As a device manufacturer serving orthopedic spine surgeons and interventional pain specialists, Aurora operates in the regulated medical device market and markets its solutions to hospital systems and ambulatory surgical centers. The company provides customer support and technical guidance to healthcare providers.

Thuasne USA, headquartered in Bakersfield, California, is the American subsidiary of the Thuasne Group, a family-owned French medical device manufacturer with 175+ years of heritage. The company specializes in orthopedic braces, orthotic devices, and therapeutic solutions designed to improve mobility and manage musculoskeletal pain. Operating as an integrator of acquired U.S. companies including Lantz Medical, Townsend Design, Quinn Medical, and Corflex Global, Thuasne USA manufactures prescription-grade custom and off-the-shelf orthotic products. Key product lines include the Rebel Reliever and Rebel Ligament knee braces, SLEEQ AP+ back support systems, SpryStep® ankle-foot orthoses (AFO), and custom rehabilitation splinting with static and dynamic motion capabilities. The company also offers medical compression hosiery and specialized orthotic solutions for post-operative recovery, chronic pain management, sports injuries, and pediatric patients. Thuasne USA maintains FDA compliance and PDAC approval, emphasizing quality, innovation, and patient-centric care across orthopedic, neurological, and vascular applications.

The Ellen Meadows Prosthetic Hand Foundation is a 501(c)(3) nonprofit organization founded in 2005 that designs, manufactures, and distributes the LN-4 mechanical prosthetic hand free of charge to amputees worldwide. The foundation has distributed over 87,000 hands across 100+ countries and 6 of 7 continents. The LN-4 hand is a mechanical prosthetic device engineered for functionality and accessibility in resource-limited settings and developing nations. The organization operates through three distribution models: one-time international fitting events, partnerships with in-country ambassador organizations, and response to individual requests. The LN-4 hand serves as both a primary prosthetic solution for recipients without access to advanced prosthetics and as a bridge device for patients on waiting lists for more sophisticated limbs. The foundation works with Rotary International and other global partner organizations to identify and fit recipients. All prosthetics are provided at no cost to recipients, supported by donor funding and volunteer efforts. The foundation combines mechanical engineering expertise with international logistics and clinical fitting capabilities to deliver prosthetic solutions in underserved markets.

Amplify Surgical is a medical device company specializing in minimally invasive solutions for lumbar spine surgery. The company develops advanced endoscopic and dual-expanding technologies designed to enhance surgical flexibility, visualization, and patient outcomes in spine interventions. Key product offerings include the dualPortal® system, a novel two-portal endoscopic approach enabling surgeons to perform a wider array of lumbar procedures with improved learning curve and efficacy, and the dualX® family of dual-expanding interbody fusion systems (dualX®Slim for TLIF procedures and dualX® LLIF solution) designed for various fusion techniques while minimizing neural retraction. These minimally invasive platforms enable spinal restoration through endoscopic or percutaneous approaches. The company has documented treatment of over 1,000 spinal levels and regularly hosts educational events including the annual Endoscopic Spine Symposium to advance surgeon training and clinical adoption of these technologies.

Hanson Medical specializes in the design and manufacture of high-quality soft-solid silicone implants for cosmetic and reconstructive surgical applications. The company offers an extensive range of pre-fabricated facial implants, body contouring implants, and carving blocks manufactured from long-term implantable silicone materials. All standard implant designs are maintained in stock for immediate shipment. The company also provides custom implant design and fabrication services for cases where standard pre-fabricated options do not meet clinical specifications. In addition to implants, Hanson Medical offers professional skincare products with custom private-labeling programs available at low minimum order quantities. The company serves plastic and reconstructive surgeons, aesthetic surgery centers, and hospital surgical departments. Manufacturing capabilities include precision silicone fabrication with multiple durometer (firmness) options and custom design support. The product portfolio encompasses facial implants, body contouring implants, silicone carving blocks for surgeon customization, and skincare lines. All products are manufactured from materials suitable for long-term surgical implantation.

Surgikor Implants is a B2B dental implant supplier specializing in world-class implant dentistry products and clinical education. Based in Los Angeles and sourcing from Germany, the company delivers a comprehensive range of dental implant systems, prosthetic components, surgical instruments, and regenerative materials. Product lines include the Versatile™ Hex, Immediate™ Hex, Fixation™, and Solution™ implant systems; healing abutments and impression transfers; surgical kits for implant placement, guided surgery, and bone grafting; and supporting devices such as implantology motors and piezosurgery systems. Surgikor offers bone graft materials and pericardium membranes for tissue regeneration, along with custom milling and surgical guide services. The company emphasizes clinical education through courses on bone grafting, dental implant procedures, and soft tissue surgery, guided by an advisory board of recognized implant dentistry professionals. Surgikor positions itself as a partner for dental practices seeking to enhance implant treatment delivery with convenient, financially compatible solutions backed by comprehensive clinical support and training.

Atlas International is a B2B distributor and supplier of orthopedic and podiatric materials, equipment, and consumables. The company specializes in casting supplies, orthotic materials, foot care products, and related equipment for orthopedic practices, podiatrists, prosthetists, and orthotists. Product lines include casting supplies (plaster and fiberglass systems), orthotic plastics, foot products and insoles, soft goods and bracing devices, shoe findings and soling materials, glues and abrasives, DME (durable medical equipment), and specialized tools and machinery for orthopedic fabrication and finishing. Atlas carries branded products from manufacturers such as Oscimed and Landis. The company serves the orthopedic, podiatric, and prosthetic/orthotic (O&P) communities with consumables, materials, and equipment necessary for patient care, custom device fabrication, and clinical operations. Distribution appears to be US-based with focus on supporting clinical practitioners and fabrication laboratories.

Corentec is a global orthopedic medical device manufacturer specializing in hip and knee joint replacement systems and related surgical solutions. The company positions itself as a value-oriented provider offering high-quality orthopedic products at competitive pricing between premium brand names and entry-level manufacturers. Primary product lines include the BENCOX hip system, EXULT and LOSPA revision knee systems, and Cortinium technology utilizing Directed Energy Deposition (DED) manufacturing for advanced implant solutions such as the Bencox 'Mirabo Z Cup'. Corentec serves orthopedic surgeons and hospitals globally, with manufacturing and distribution capabilities across multiple regions. The company emphasizes sophisticated engineering, intuitive design, and quality assurance in product development. Corentec operates the FiRST Academy, a professional medical education program focused on surgeon training and continuing education. The company maintains a commitment to regulatory compliance and product quality standards required for international orthopedic device distribution. Corentec's business model targets healthcare systems seeking cost-effective joint replacement solutions without compromising clinical outcomes or product durability.

Dental Evolutions, Inc. is a dental implant innovator specializing in the Implanova® system, a comprehensive implant platform developed through 60+ years of accumulated implant research and 3 years of full-time engineering utilizing CAD/CAM and advanced 3D printing technology. The company manufactures a complete line of dental implant components including self-osteotomizing, self-grafting implants; restorative abutments and healing caps; fixed and removable attachment prosthetics; and specialized surgical tools and drills. The Implanova® system features patented and patent-pending designs that differentiate it from established competitors, with particular emphasis on full arch implant solutions. Products are designed for seamless compatibility across implant sizes and restoration modalities, supporting both cement and screw retention. The company serves dental implant practitioners and appears to offer educational resources and training through affiliated channels. Manufacturing capabilities include precision CAD/CAM design and 3D printing fabrication for custom prosthetic components and surgical instruments.

Berkeley Advanced Biomaterials (BAB) is a licensed tissue bank founded in 1996, accredited by the American Association of Tissue Banks (AATB). The company manufactures allograft, synthetic, and bioactive biologic solutions for orthopedic and soft tissue surgical applications. BAB focuses on cost-effective, clinically relevant products designed for bone regeneration, reconstruction, and soft tissue repair. The company serves surgeons and healthcare providers across orthopedic, spine, sports medicine, and general surgery specialties. As a regulated biologics manufacturer, BAB operates under tissue banking standards and compliance frameworks required for allograft processing and distribution. The company's product portfolio includes allograft bone and cartilage products, synthetic bone substitutes, and bioactive scaffolds for surgical implantation. BAB emphasizes clinical relevance and cost-effectiveness, positioning products as alternatives to autograft and xenograft materials while maintaining rigorous quality and safety standards.

Glidewell Dental is the world's largest dental laboratory and digital dentistry solutions provider, headquartered in Irvine, California. Founded in 1970, the company employs 4,300–5,000 professionals and delivers custom restorative dental prosthetics including crowns, bridges, dentures, and implants. Leveraging advanced digital workflows, 3D printing, and CAD/CAM milling technology, Glidewell specializes in high-quality, cost-effective solutions accessible to practitioners of all practice sizes. Flagship products include BruxZir Solid Zirconia restorations, Glidewell HT dental implants, Simply Natural Digital Dentures, and Comfort H/S bite splints. The company also offers glidewell.io, a comprehensive in-office milling and design suite for same-day restorations, alongside clinical support, continuing education (AGD PACE-certified), and research-driven innovations. Glidewell serves dentists globally through U.S. lab facilities and international offices, backed by a no-fault remake warranty and knowledgeable technical support.

Aspen Medical Products is a US-based manufacturer of spinal bracing and orthopedic support devices. The company designs and markets a comprehensive portfolio of cervical, thoracic, lumbar, and sacral orthoses (braces) for pain management, acute care, motion restriction, and postoperative support. Product lines include the VRTX System (a modular total-spine solution), Horizon PRO series (thoracolumbosacral orthoses), and specialty products such as the Popple LSO (maternity back brace), Vista MultiPost therapy collars, and extremity supports. Aspen serves orthopedic surgeons, physiatrists, chiropractors, and other physician specialties treating spinal conditions, trauma, post-surgical recovery, and chronic pain. The company offers DME (durable medical equipment) billing support and clinical training. With 25 years of research-driven design, Aspen emphasizes therapeutic motion restriction, skin integrity, posture correction, and muscle spasm reduction. Products are marketed through direct B2B channels, physician representatives, and an e-commerce platform. The company maintains FDA compliance and ISO certifications for medical device manufacturing.

Dimensional Bioceramics manufactures advanced bioceramic orthopedic solutions for skeletal repair and bone void filling. The company specializes in next-generation calcium phosphate and calcium sulfate bone graft substitutes designed for orthopedic surgeons. Product lines include OsteoRepair, a high-performance calcium phosphate cement for cancellous bone defects with superior compression strength and wet-field handling; OsteoRepair Hybrid, a proprietary calcium phosphate-calcium sulfate blend engineered for challenging cancellous bone with faster remodeling characteristics; and OsteoResolve, a medical-grade calcium sulfate bone void filler indicated for infected bone sites that resorbs and remodels during healing. All products are biodegradable and biocompatible. The company brings decades of expertise in orthobiologic product development from concept through commercialization and maintains active R&D programs in bioceramic advancement. Dimensional Bioceramics serves orthopedic surgeons and surgical centers with products meeting clinical standards for skeletal repair applications.

Subchondral Solutions manufactures orthopedic implants for the treatment of osteochondral defects and subchondral bone insufficiency. The company's primary product, S-Core®, is a bone fixation and soft tissue augmentation implant designed to address full-thickness osteochondral fracture defects, trabecular fractures, micro-cracks, and osteochondritis. S-Core® is placed below the hyaline cartilage surface to eliminate contact with sensitive articulating surfaces while providing structural integrity to the subchondral bone and preserving joint function. The implant is available in multiple sizes (4.0mm–10.0mm) to address lesions of varying dimensions. S-Core® features fenestrations for secure fixation and is used with S-Fibre® Dual-Armed Suture and a standard T-10 driver for implant placement. The device is designed to provide superior fixation and bone integration with proven strength at time zero. Target markets include orthopedic surgeons performing joint preservation and cartilage repair procedures.

Empirical Spine, Inc. manufactures the LimiFlex Dynamic Sagittal Tether, an FDA-approved (PMA, February 12, 2026) minimally invasive spinal implant designed as a motion-preserving alternative to spinal fusion for patients with Grade I lumbar degenerative spondylolisthesis with stenosis. The device is inserted without screws, augments the posterior tension band to restore natural segmental motion and stability, and maintains lordosis while providing elastic resistance to flexion. LimiFlex engages selectively during flexion (unlike interspinous spacers) to avoid excess spinous process loading and is compatible with current decompression techniques. The implant targets the substantial clinical need for alternatives to traditional fusion surgery, which carries documented drawbacks including invasiveness, high costs, and risk of adjacent-level degeneration (occurring in 30–50% of fusion patients within 5–10 years). Empirical Spine positions LimiFlex for orthopedic surgeons managing degenerative lumbar spine disease in hospital and ASC settings.

Providence Medical Technology, Inc. is a privately held medical device manufacturer based in Pleasanton, CA, specializing in spinal fusion implants and surgical systems for cervical and lumbar spine applications. The company develops tissue-sparing posterior fusion solutions designed to improve clinical outcomes and prevent surgical failures through total segmental fusion (TSF) approaches. Providence's cervical portfolio includes the CORUS™ LevelOne system, which integrates surgical access, bone preparation, decortication, graft delivery, and stabilization in sterile, single-use packages. The CORUS™ PCSS (Posterior Cervical Stabilization System) represents their signature cervical offering, supported by landmark multicenter randomized controlled trials published in peer-reviewed journals. The lumbar product line comprises the CORUS™-LX LevelOne and CORUS™ Navigation Access System, designed for posterior lumbar fusion with facet stabilization as an adjunct to interbody fusion. These lumbar systems are compatible with robotic navigation platforms to enhance surgical precision. Providence also offers ancillary products including CAVUX® cervical cages, ALLY® screw systems, ENTRUS® allograft bone, and the DiViNE™ Portal System for cervical access. The company's solutions are approved and in use at over 2,600 hospitals and facilities with more than 20,000 cases performed. Providence supports surgeon adoption through comprehensive training programs, including case simulation, anatomical models, live case observation, and peer-to-peer teleconference platforms. The company maintains clinical publications and prospective randomized controlled trials (Fuse Study, ILIF Lumbar Study) demonstrating efficacy and safety. Providence markets to spine surgeons, hospital surgical centers, and orthopedic facilities across the United States and internationally.

Biogennix is a medical device manufacturer specializing in advanced synthetic bone graft products for orthopedic and spinal surgery. The company's core technology platform, TrelCor®, features nano-sized surface architecture designed to optimize cell attachment and promote bone formation. Biogennix offers moldable, hydrated bone graft materials under product lines including Agilon®, engineered to improve surgical outcomes in spinal and orthopedic procedures. The company operates a distributor-based commercial model, partnering with specialized distributors in the spinal surgery space. Products are synthetic bone grafts intended as alternatives to autograft and allograft options, addressing a significant market need in orthopedic surgery where bone graft substitutes are critical for fusion procedures and defect management. Regulatory status and specific 510(k) clearances are not detailed on the accessible website content, though the company markets products as advanced medical devices for clinical use.

Teh Lin Prosthetic & Orthopaedic, Inc. is a multinational prosthetics and orthopedic device manufacturer founded in 1960, serving over 50 countries through 100+ branches with 1,000+ experts. The company specializes in customized prosthetic solutions for all levels of amputation, including comprehensive lower limb (knee joints, hip joints, feet joints), upper limb, and pediatric prosthetic systems. Product lines include microprocessor knees, pneumatic knees, hydraulic knees, and mechanical knee joints; hip joints; specialized feet joints; sockets, liners, and accessories; and pediatric-specific prosthetics. The company also manufactures silicone and gel-based SILFIT liners for prosthetic applications. Orthopedic offerings include scoliosis braces (ScoliBrace). Featured products include the C-TK-4PSOIC, A-TGK-5PSOIC, C-RAY-RP1, A-TGK-4P00AW, C-TK-4P02, and C-XTR-X60 prosthetic components. Teh Lin operates a distribution network and maintains TL OLINK+ Fit Centers for prosthetic fitting and training. The company provides comprehensive solutions addressing lower limb, upper limb, and pediatric prosthetic needs for amputees across diverse clinical and functional levels.

RX Orthotic Inc is a custom orthotic manufacturer and supplier specializing in personalized foot orthotics designed for clinical professionals, podiatrists, and healthcare practitioners. The company serves over 300 professional clients and provides cutting-edge orthotic solutions using user-friendly 3D iOS scanning apps to capture patient foot data. RX Orthotic Lab offers a range of pathology-specific orthotic designs including RX Sport (for athletic performance and injury prevention), RX Gait Plate (for in-toeing and out-toeing accommodation), and RX Geriatrics (for older adults with deformities and balance issues). The company emphasizes custom fit and tailored support for patient-specific needs. RX Orthotic operates a B2B model with professional account options offering volume pricing, quick order fulfillment, and dedicated customer support. The business combines digital scanning technology with custom manufacturing to deliver personalized foot orthotic devices that address various clinical conditions and improve patient outcomes through enhanced foot alignment, cushioning, and stabilization.