Urology in Minnesota

Carbon Medical Technologies, Inc. (formerly Advanced UroScience, Inc.) designs and manufactures implantable and minimally invasive medical devices using proprietary pyrolytic carbon coating technology. Founded in 1994, CMT is one of only five organizations worldwide with a dedicated pyrolytic carbon coating facility. The company specializes in devices for urological and oncological applications, with over 25 years of clinical use across 55+ countries and treatment of more than 1.4 million patients. CMT's primary product portfolio includes Durasphere® (an injectable bulking agent for stress urinary incontinence treatment), BiomarC® fiducial and tissue markers for radiation therapy and breast lesion localization, BiomarC® Restore for post-lumpectomy guidance, and the newly launched InjecSURE® cystoscopic injection system with female-specific anatomical design for urethral injections. The company operates under ISO 13485 and cGMP-compliant quality systems, maintains a validated ISO Class 7 cleanroom, and provides contract manufacturing services including design consultation, materials expertise, cleanroom assembly, and regulatory guidance. CMT supports multiple sterilization methods and manages the full product lifecycle from development through final delivery, positioning itself as a specialized provider for minimally invasive urology and oncology procedures.

Resolution Medical is a medical device development and manufacturing partner specializing in complex catheter delivery systems, active implantable devices, and component manufacturing. The company serves structural heart, cardiology, vascular, heart failure (VAD), neuromodulation, electrophysiology, and additional specialty markets including ENT, neurology, urology, oncology, endoscopy, and robotics. Core capabilities span the full product lifecycle: concept and design development, BioSimulation and testing with cardiovascular visualization in pressurized heart models, New Product Introduction (NPI) with design-for-manufacturing optimization, and end-to-end manufacturing from prototyping through commercial production. Resolution Medical operates specialized clean rooms, sterile packaging, labeling, and distribution infrastructure. In structural heart, the company develops implants and catheter delivery systems for mitral, tricuspid, aortic, and pulmonary valve interventions, as well as shunts, stents, closure devices, and embolic protection. Cardiology and vascular expertise includes complex delivery platforms, imaging and sensing catheter systems for peripheral, neurovascular, and cardiovascular applications, DVT/PE management, drug delivery, and flow management. Heart failure capabilities encompass VAD pump development, drivelines, and deployment systems. Neuromodulation focus includes Class III active implantables: implantable pulse generators (IPGs), leads, headers, adapters, and subassemblies for spinal cord stimulation, deep brain stimulation, vagus nerve stimulation, and peripheral nerve modulation. Electrophysiology specialization covers diagnostic mapping and energy delivery catheters with modalities including pulsed field ablation (PFA), RF energy, cryotherapy, and vapor therapy. The company maintains a quality management system per ISO 13485:2016 and operates under FDA guidelines. Resolution Medical was recently acquired by Resonetics (2025) and operates with 100+ engineers backed by 1,000+ combined years of experience.

Vitacon US, LLC is the North American sales, service, and contract manufacturer for Vitacon AS (Trondheim, Norway). The company specializes in the design, development, and distribution of the VitaScan LT series—fully automatic USB ultrasound bladder scanners. The VitaScan LT portfolio includes models eVue, cVue, C5, and C6, which employ dual-plane, auto-rotating, and auto-tracking ultrasound technology to calculate bladder volume in real-time without requiring sonographer training. These portable instruments are marketed for long-term care, nursing homes, skilled nursing facilities, acute care, emergency departments, surgery centers, and urology clinics. Vitacon US provides comprehensive support including calibration services, warranty registration, RMA processing, and technical documentation. The company maintains both shipping and mailing addresses in Minnesota and operates an online store for product sales and quotations.

Uromedica, Inc. is a medical device manufacturer specializing in minimally invasive surgical therapies for the treatment of stress urinary incontinence (SUI). The company develops and markets two primary product lines: ProACT (adjustable continence therapy for men) and ACT (adjustable continence therapy for women). ProACT is indicated for treatment of male SUI resulting from radical prostatectomy or transurethral resection of the prostate and is commercially available in the United States. ACT is designed for treatment of female SUI resulting from intrinsic sphincter deficiency; it has received CE Mark approval for European markets, Canadian licensing, and Australian therapeutic goods registration, but is classified as investigational in the United States. Both systems utilize silicone balloon technology and are designed as passive therapies requiring no patient manipulation for normal voiding. Key differentiators include minimally invasive placement via small incisions, office-based adjustability without additional surgery, reversibility with office-based removal, and passive operation. The company emphasizes physician and patient education, maintains a physician locator network for treatment access, and provides safety information and regulatory documentation. Manufacturing and regulatory compliance align with medical device standards applicable to implantable urological products.

Annex Medical, Inc. is an original equipment manufacturer (ODM) specializing in endoscopy devices and surgical instruments for urology since 1988. Based in Hopkins, Minnesota, the company designs and manufactures single-use urological devices including stone baskets, grasping forceps, biopsy forceps, cytology brushes, and cutting electrodes. The company offers comprehensive manufacturing capabilities including nitinol shape-setting, wire forming, swaging, injection molding, laser welding, robotic manufacturing, and microscopic assembly. Quality assurance processes include 100% proof testing, automated vision system inspection, and clean room packaging. Annex Medical provides EO sterilization services at multiple contract sterilizers and also operates Sacred Heart Medical, an in-house product line for urology devices. The company serves surgical device manufacturers and healthcare providers with custom device solutions.

Francis Medical develops the Vanquish® Water Vapor Ablation System, an FDA-cleared, minimally invasive medical device designed for targeted thermal ablation of prostate tissue via transurethral approach. The system uses sterile water vapor energy to treat localized prostate cancer and benign prostatic conditions. Founded in 2018 and based in Maple Grove, Minnesota, Francis Medical specializes in urological oncology solutions that minimize long-term side effects associated with traditional prostate treatments. The Vanquish System is designed for outpatient use with transurethral delivery incorporating standard cystoscopy and transrectal ultrasound. Clinical data from the VAPOR 2 multi-center pivotal study (n=235) demonstrates 91% clearance of targeted MRI-visible disease, low rates of urinary incontinence (2.7% Grade 2 or higher), low rates of erectile dysfunction, and high patient satisfaction (93% extremely satisfied/satisfied at 12 months). The system treats prostate lesions in any anatomical location including apex, anterior, and transition zone. Commercial adoption is expanding across U.S. surgery centers.

NorthStar Surgical, Inc. is a specialty surgical products distributor and manufacturer's representative group serving the Upper Midwest, including Minnesota, North Dakota, South Dakota, Wisconsin, Iowa, and Nebraska. The company provides surgical products and solutions across multiple surgical specialties: Cardiac, ENT (Otorhinolaryngology), General Surgery, Gynecological, Neurosurgery, Orthopedic, Plastic Surgery, Vascular, and Urological Surgery. NorthStar's sales force brings over 100 years of combined experience in specialty surgical product sales and distribution. The company operates as both a direct distributor and rep group, positioning itself as a regional leader in the specialty surgical market. Based in Edina, Minnesota, NorthStar serves hospitals, surgical centers, and physician practices throughout the region. The company maintains direct sales support, customer service, and operations management to facilitate orders, technical support, and relationship management with healthcare facilities.