Francis Medical

Francis Medical develops the Vanquish® Water Vapor Ablation System, an FDA-cleared, minimally invasive medical device designed for targeted thermal ablation of prostate tissue via transurethral approach. The system uses sterile water vapor energy to treat localized prostate cancer and benign prostatic conditions. Founded in 2018 and based in Maple Grove, Minnesota, Francis Medical specializes in urological oncology solutions that minimize long-term side effects associated with traditional prostate treatments. The Vanquish System is designed for outpatient use with transurethral delivery incorporating standard cystoscopy and transrectal ultrasound. Clinical data from the VAPOR 2 multi-center pivotal study (n=235) demonstrates 91% clearance of targeted MRI-visible disease, low rates of urinary incontinence (2.7% Grade 2 or higher), low rates of erectile dysfunction, and high patient satisfaction (93% extremely satisfied/satisfied at 12 months). The system treats prostate lesions in any anatomical location including apex, anterior, and transition zone. Commercial adoption is expanding across U.S. surgery centers.