Synergy Biomedical

Synergy Biomedical, LLC manufactures synthetic bioactive bone graft materials based on 45S5 bioactive glass technology. The company specializes in engineered BioSphere® particles—spherical, bimodal-sized bioactive glass formulations designed to optimize bone healing in orthopedic and spinal applications. Product lines include BioSphere® PUTTY (putty-form bone graft substitute), BioSphere® MIS II (minimally invasive delivery system for spinal fusion), BioSphere® Flex (flexible bone graft), BioSphere® FLEX SP (spinal variant), and BioSphere® Flex SP Extremities (extremity-specific formulation). The company serves orthopedic surgeons, spinal surgeons, and distributors in the US market. Synergy emphasizes bioactive glass composition, particle morphology optimization, and clinical in vivo bone healing outcomes. The company maintains a quality system and operates from Wayne, Pennsylvania. Distribution partnerships are available. No specific FDA 510(k) or ISO certifications are mentioned on the primary web pages provided, though a dedicated Quality System page exists on the site.