Signum Surgical Limited

Signum Surgical is an Irish medtech company specializing in minimally invasive surgical solutions for colorectal diseases, particularly anal fistula treatment. Founded in 2014 and based in Galway, the company develops the BioHealx implant—a helical, barbed, bioabsorbable implant designed to close fistula tracts through tissue apposition while preserving anal sphincter function and continence. The implant is delivered via a single-use, pre-loaded disposable device that rotates the helical structure into soft tissue at the fistula source, eliminating exposure to the ano-rectal canal. Signum Surgical addresses a significant clinical need: approximately 90,000 annual surgical procedures are performed in the U.S. alone for anal fistula treatment, yet existing options carry high recurrence rates, healing complications, and risk of permanent incontinence. The BioHealx approach offers FDA-cleared technology designed to optimize outcomes, promote primary healing, and reduce recurrence—all within a single procedure—thereby improving patient quality of life and surgical efficacy.