SIGN Fracture Care International

SIGN Fracture Care International is a humanitarian organization headquartered in Richland, Washington, that manufactures and donates orthopedic implants and surgical instruments to developing countries. The organization combines surgeon education with donated implants to build sustainable orthopaedic capacity in low- and middle-income countries. SIGN designs, manufactures, and distributes intramedullary nails (Standard SIGN Nail, Fin Nail, Pediatric Fin Nail) and FX Plates at its Richland, Washington facility. The SIGN System is specifically engineered for low-resource hospital environments and does not require expensive imaging equipment or electricity. Operating in 60 countries across 459 hospitals, SIGN has provided care to over 487,600 patients. The organization's model emphasizes fracture treatment that enables rapid patient mobilization, avoiding the long-term disability associated with traction and plaster cast immobilization in resource-limited settings. SIGN implants are designed for reliability and cost-effectiveness in treating trauma injuries, particularly among the working poor in developing regions where untreated fractures lead to permanent disability and economic hardship.