PLEXAA LTD

Plexāā is a UK-based medical technology company specializing in preoperative optimization and surgical prehabilitation. The company's flagship product, BLOOM⁴³, is a Class II, FDA-registered, sensor-controlled wearable thermal preconditioning device designed to enhance tissue blood flow before breast surgery. The device uses a patented intermittent thermal algorithm to stimulate heat shock proteins and induce local carbon monoxide release, a potent vasodilator that improves microcirculation. Clinical trials demonstrate BLOOM⁴³ reduces reoperation rates by 50%, outpatient follow-ups by 70%, and skin necrosis risk by 24% absolute reduction. The BLOOM⁴³ platform combines the wearable device with a companion smartphone app offering evidence-based prehab and rehab guidance, patient support communities, symptom tracking, and clinical photo documentation. The app is free and available for iOS and Android, targeting breast surgery patients. BLOOM⁴³ is drug-free, non-invasive, and worn inside a bra for three hours the night before surgery. The company is expanding into the U.S. market with $4.5M in funding and exploring applications across additional surgical specialties to establish prehabilitation as standard care.