Penumbra, Inc.

Penumbra, Inc. is a global medical device company headquartered in Alameda, California, with manufacturing and service facilities in Livermore, CA and Salt Lake City, UT. The company specializes in innovative catheter-based systems for minimally invasive treatment of acute ischemic stroke, pulmonary embolism (PE), and venous thromboembolism (VTE). Primary product lines include the Penumbra System (mechanical thrombectomy platform) and the Lightning Flash series (aspiration catheter technology for PE and clot management). The Penumbra System RED comprises reperfusion catheters, separators, aspiration tubing, and aspiration pump components designed for interventional neuro-endovascular procedures treating large vessel occlusion within the intracranial circulation (internal carotid, middle cerebral M1/M2, basilar, and vertebral arteries) within 8 hours of symptom onset. Lightning Flash 3.0 represents the latest generation CAVT (Controlled Aspiration and Vacuum Thrombectomy) technology for acute PE and venous thrombus management. Products are indicated for patients ineligible for or refractory to intravenous thrombolytic therapy. The company maintains global distribution through offices in Europe, Latin America, and Canada. Penumbra devices are single-use, sterile systems requiring specialized physician training in interventional endovascular techniques. Manufacturing capabilities include precision catheter coating, sterile packaging, and quality systems supporting regulatory requirements for FDA-cleared and CE-marked devices. The company serves interventional radiology, neurovascular, and vascular surgery specialties in hospital and interventional center settings.