Onpharma Company

Onpharma is a dental medical device manufacturer specializing in local anesthetic buffering solutions for dental practices. The company's flagship product is the Onset EZ Pen, a disposable, single-use device that buffers local anesthetic cartridges by delivering 8.4% sodium bicarbonate solution to raise pH toward physiologic neutral levels prior to injection. The Onset EZ Pen is designed for chairside use in operative dentistry and oral surgery, requiring no assembly or formal training. Each pen delivers 30 precise buffering doses and maintains sterility for up to 30 days after opening. Clinical benefits include faster anesthetic onset (reduced time to patient numbness), reduced injection pain and stinging sensation, and increased anesthetic predictability—particularly beneficial for anxious patients and those with infections. The system is compatible with common dental local anesthetics including articaine, lidocaine, prilocaine, and mepivacaine. Onpharma markets the Onset EZ Pen as the #1 buffering solution in dentistry, with over 10 million doses delivered to dental practices. The device is fully disposable and eliminates extra packaging and sharps waste, positioning it as an efficient, high-volume solution for dental practices seeking to enhance patient comfort and clinical productivity.