NEXUS MEDICAL, LLC

Nexus Medical, now part of Avanos Medical, specializes in anti-reflux needleless connectors for infusion therapy. The company's flagship product line, the TKO (Therapy Keep Open) series, features bidirectional, pressure-sensitive diaphragm technology designed to minimize reflux during intravenous infusion and reduce central venous access device (CVAD) and peripherally inserted central catheter (PICC) line occlusions. The TKO-6PHV model is specifically formulated for home infusion applications. Clinical evidence from peer-reviewed publications demonstrates that TKO connectors achieve an 89% success rate with a single IV per patient visit and reduce CVAD occlusion rates by up to 69% compared to neutral or negative needleless connectors. The technology is recognized in the 2024 Infusion Nursing Society (INS) Standards of Practice as producing the least amount of reflux among available connector types. Nexus Medical markets its products to hospital systems, home infusion providers, and infusion nursing programs seeking to reduce pharmacy costs, medical supply waste, and nursing time associated with catheter occlusion management. The company's research publications appear in the American Journal of Health System Pharmacists and are cited in professional standards documents.