Midwest Interventional Systems

Midwest Interventional Systems (MIS) is a vertically integrated, FDA-registered medical device contract manufacturer and design partner specializing in catheter systems and minimally invasive device components. The company designs and manufactures custom medical balloons (non-compliant, semi-compliant, and compliant variants) and medical extrusions (single-lumen to complex multilumen tubing) for interventional and endovascular applications. MIS serves 100+ minimally invasive device companies spanning neurovascular, atrial fibrillation, endoscopy, and other specialties. The company operates three core business units: Components (off-the-shelf and custom balloons and extrusions via online design tools), Design Services (concept-to-commercialization catheter engineering with a dedicated Co-Lab for rapid prototyping), and Manufacturing (pilot through full-scale contract manufacturing with in-house capabilities). Key offerings include IQueue (proprietary online extrusion designer for rapid custom ordering), Balloon Designer, Catheter Designer, and an online component store with 24-hour shipping and $50 minimum orders. MIS maintains ISO 14385:2016 certification and FDA registration. The company employs catheter engineers with 10+ decades of combined expertise and follows a proven 5-phase development methodology. Notable clients and testimonials reference work with neurovascular innovators, endoscope manufacturers, atrial fibrillation device companies, Mayo Clinic physician innovators, and leading MedTech firms.