InterVene Inc

InterVene, Inc. is a medical device company specializing in interventional treatment of venous pathology, specifically venous in-stent restenosis (ISR) and thrombotic venous obstructions. The company has developed the first fully integrated mechanical thrombectomy system designed to address clinical challenges associated with venous ISR and residual thrombotic venous obstructions and occlusions where current therapeutic options (balloon angioplasty, stent relining) have proven ineffective. ISR is a frequent complication following venous stenting procedures, with published literature indicating substantial patient populations develop ISR with organized, non-acute thrombus composition. The company also addresses postthrombotic syndrome (PTS), a long-term sequela of deep vein thrombosis affecting 20-50% of DVT patients, which presents with persistent leg swelling, pain, skin changes, and in severe cases, venous leg ulcers. Current conservative treatment options for PTS are limited and include anticoagulation therapy, compression stockings, leg elevation, and lifestyle modifications, with no definitive cure available. InterVene's mechanical thrombectomy platform represents an innovation in addressing these persistent unmet clinical needs in venous intervention.