InspireMD, Inc.

InspireMD, Inc. is a medical device manufacturer specializing in carotid intervention and stroke prevention. The company develops and markets the CGuard® and CGuard® Prime carotid stent systems, which feature dual-layer designs combining a conformable self-expanding stent with a protective non-metallic MicroNet™ mesh covering. The CGuard Prime system is indicated for improving carotid luminal diameter in high-risk patients requiring carotid revascularization, addressing the significant clinical problem of plaque prolapse and late embolization during carotid artery stenting (CAS) procedures. According to pivotal trial data (C-GUARDIANS), CGuard Prime demonstrated 0.95% 30-day and 1.93% 1-year major adverse event rates (composite of death, any stroke, or myocardial infarction), among the lowest independently adjudicated rates in carotid stenting literature. The system is designed for vessel reference diameters between 6.4 mm and 9.0 mm and is used in conjunction with embolic protection devices including Abbott Emboshield NAV6 or Medtronic Mo.Ma Ultra. InspireMD maintains USA headquarters in Miami, Florida, with manufacturing operations in Israel and EU representation through Obelis s.a. in Brussels. The company serves interventional cardiologists, vascular surgeons, and endovascular specialists globally, with regulatory clearance for sale in the United States and Europe. Product design emphasizes SmartFit flexibility for variable anatomy and MicroNet mesh for enhanced plaque prolapse prevention.