Centerline Biomedical

Centerline Biomedical develops intraoperative navigation technology for endovascular and interventional procedures. The company's flagship product, IOPS® (Intra-Operative Positioning System), is a 510(k)-cleared navigation platform that provides real-time 3D color image guidance as an alternative to conventional X-ray fluoroscopy. IOPS® is designed to mitigate occupational and patient radiation exposure in interventional cardiology, vascular surgery, and complex endovascular procedures. The system offers interactive navigation, high-quality 3D imaging, and portability compared to traditional 2D fluoroscopy-based guidance. Clinical evidence presented on the site documents significant occupational hazards associated with fluoroscopy exposure, including radiation-induced cataracts, brain tumors, and orthopedic issues among interventionalists. IOPS® targets procedures estimated at 4 million annually in the United States. The company collaborates with major medical institutions including Cleveland Clinic, the U.S. Air Force 59th Medical Wing, and the U.S. Army Institute of Surgical Research, indicating validation in both civilian and military surgical settings. The technology is positioned for vascular surgeons, interventional cardiologists, and trauma surgeons performing endovascular therapy, aortic procedures, and complex case management where radiation dose is a clinical and occupational concern.