Functional Diagnostics in Pennsylvania

DGH Technology, Inc. is a US-based manufacturer of ophthalmic diagnostic devices specializing in corneal pachymetry and advanced ultrasound imaging systems for eye care professionals. The company manufactures all products on-site at its Pennsylvania facility. The product portfolio includes pachymeters (Pachmate 2, Pachette 4) for measuring central corneal thickness—critical for glaucoma diagnosis, suspect assessment, and surgical planning—and ultrasound scanning systems (ScanMate Flex, ScanMate A, ScanMate B) offering A-scan and B-scan capabilities with multiple probe configurations. ScanMate Flex provides three probe options on a single platform; ScanMate A delivers ultra-portable A-scan functionality; ScanMate B offers ultra-portable B-scan imaging. All systems feature intuitive software with minimal learning curve, real-time data processing including mean and standard deviation calculations, and are designed for high-volume clinic use. The company emphasizes affordability, reliability, and ease of operation for optometrists, ophthalmologists, and ophthalmic technicians. Customer support is provided Monday–Friday, 8:00 AM to 4:00 PM EST by trained technicians. Products are widely adopted in clinical practices, academic institutions, and screening environments for glaucoma evaluation, corneal disease assessment, and intraocular lens calculations. The company exhibits at major industry conferences including ASCRS, ARVO, and AOA.

InfraScan, Inc. is a medical device manufacturer specializing in portable brain imaging for rapid detection of intracranial bleeding and traumatic brain injury. The company develops and commercializes the Infrascanner®, a portable screening device using Near-Infrared (NIR) spectroscopy technology to identify patients with intracranial hematomas who require immediate CT imaging and neurosurgical intervention. The Infrascanner 2500 enables non-invasive, bedside assessment of head trauma patients in emergency departments, intensive care units, military field hospitals, ambulance services, and remote locations without requiring transport to imaging facilities. Over 200 devices have been deployed to all USMC Battalion Aid Stations as part of standard trauma kits. The technology was invented by Dr. Britton Chance (University of Pennsylvania) and Dr. Claudia Robertson (Baylor College of Medicine), validated in clinical studies of 305 patients at Baylor College of Medicine. FDA-cleared and CE-marked, the Infrascanner has been studied at distinguished teaching hospitals and specialty pediatric facilities throughout the U.S. and has demonstrated clinical utility in both adult and pediatric populations internationally. The device addresses a critical gap in point-of-care neuroimaging, particularly valuable in military trauma settings, remote locations, and resource-limited environments where immediate CT access is unavailable. InfraScan holds regulatory clearances enabling use across emergency medicine, neurocritical care, military medicine, and sports medicine applications.

Manheim Medical Supply is a privately owned and operated medical supply distribution company serving skilled nursing facilities, assisted living facilities, and hospices throughout Central Pennsylvania. The company provides comprehensive supplies and services including wound care, diagnostics equipment, incontinence products, linen, nursing supplies, ostomy supplies, rehabilitation equipment, nutritional products, and pharmacy items. Manheim Medical Supply's experienced team offers personalized product selection assistance and consultative services to help healthcare facilities navigate industry changes. The company has built a reputation for integrity, quality products, and long-term customer partnerships.

Instanosis Inc. develops high-sensitivity diagnostic technology for rapid drug detection in clinical, harm reduction, forensic, and law enforcement applications. The company manufactures FDA-cleared, CLIA-waived dipstick and test strip products for detecting fentanyl, xylazine, and nitazene in human urine and other biological samples. Products are reported to be 25 times more sensitive than competitor alternatives and have been validated in clinical settings with over 1,000 urine samples. Instanosis supplies hospital-grade drug detection systems for healthcare facilities, rapid response kits for outreach and shelters, field testing solutions for forensic teams, and distributes through GPOs and medical distributors. The company is NIH-funded and manufactures all products in the United States. Their diagnostic portfolio includes lateral flow assays and monoclonal antibody reagents (anti-fentanyl Clone H16) for ELISA and immunoassay development. The company targets clinical trial support, disease diagnosis and monitoring, overdose response, and harm reduction programs.

OraSure Technologies, Inc. is a leading developer and manufacturer of non-invasive diagnostic testing devices and oral specimen collection tools for infectious disease detection. The company's core portfolio includes rapid point-of-care tests for HIV, hepatitis C (HCV), hepatitis B (HBV), syphilis, Ebola, and COVID-19 (InteliSwab). OraSure markets products under multiple brands including OraQuick (rapid antibody tests), SureQuick (rapid tests), and proprietary specimen collection devices. The company also operates through subsidiaries: DNA Genotek (sample collection and preservation solutions for genomic, metabolomic, and microbiome research), Sherlock Biosciences (rapid diagnostic test development), and BioMedomics (sickle-cell rapid testing). Products are distributed globally through direct sales, online ordering, and healthcare provider networks. OraSure serves public health authorities, clinical laboratories, healthcare practitioners, researchers, and retail channels. The company emphasizes accessibility and decentralization of diagnostics, particularly for underserved populations and resource-limited settings. Manufacturing and quality standards align with FDA regulatory requirements and international standards. Customer support includes product training, technical documentation, and dedicated customer care with phone and email channels available for U.S. and international markets.