EEG / EMG in California

Persyst Development LLC is the worldwide leader in EEG (electroencephalography) software for clinical neurodiagnostics. The company develops and markets Persyst 15 (P15), a comprehensive Computer Assisted Review of EEG (C.A.R.E) platform that provides advanced tools for EEG data review, analysis, and monitoring. Core capabilities include automated seizure detection, spike detection, artifact reduction, and EEG trending analytics designed to support both high-volume institutions and community clinics. Persyst's seizure detection algorithm has been validated in peer-reviewed literature (Journal of Clinical Neurophysiology) as statistically noninferior to skilled human reviewers. The company also offers Persyst Mobile, the first FDA-cleared EEG monitoring and review application for mobile devices, enabling remote access to EEG data. Persyst is integrated with and sold/supported by every major EEG hardware manufacturer, including Micromed, Natus, Nihon Kohden, Cadwell, and Compumedics. The software is recognized as the standard of care, with adoption at 211 of 233 US News-ranked neurology and neurosurgery centers. The company maintains a strong commitment to clinical research and scientific validation, publishing findings in peer-reviewed journals and hosting educational events such as Persyst Grand Rounds.

Medeia Inc is a manufacturer and distributor of neurodiagnostic and cardiovascular physiological monitoring systems. Founded in 1992, the company specializes in state-of-the-art biometric hardware and software for autonomic nervous system assessment, vascular analysis, EEG/EEG-derived diagnostics, and sleep studies. Medeia's product portfolio serves neurologists, cardiologists, primary care physicians, and research institutions with comprehensive tools for objective physiological measurement, including autonomic function testing (ANS), pulse wave velocity analysis, peripheral neuropathy assessment, and neuroencephalography. The VitalScan product line addresses autonomic and vascular diagnostics; BrainView systems provide EEG and cognitive assessment; NeuroTrace offers ambulatory wireless EEG; SleepStudy delivers polysomnography; and CardioView supplies mobile cardiac telemetry. Products are designed for clinical workflow efficiency and are distributed internationally to healthcare providers and research facilities.

LVIS Corporation is a San Francisco Bay Area–based medical technology company specializing in neural information analysis and EEG diagnostics software. The company develops patented brain-imaging visualization and analysis technologies that decode brain network activity to support neurological disease diagnosis and clinical workflows. LVIS's flagship product is NeuroMatch®, a cloud-based SaaS platform that automates and enhances EEG examination, source localization, and 3D/4D brain visualization. NeuroMatch has received FDA 510(k) clearance (K250239) in the United States and MFDS regulatory clearance in South Korea. The platform addresses critical gaps in neurological healthcare capacity: the shortage of neurologists (1 per 23,259 people), sub-optimal clinical workflows, and surging demand for neurological diagnosis. LVIS is backed by prestigious academic partnerships, including Stanford Byers Center for Biodesign Faculty Fellowship, Stanford StartX incubator, and NVIDIA Inception Program support. The company has received research grants from the Stanford Spectrum Center, LivaNova, and the Epilepsy Foundation. Leadership includes neuroscience and engineering experts; the company was founded by Jin Hyung Lee, PhD. NeuroMatch was named a 2026 Edison Awards finalist. The company operates with headquarters in Palo Alto, California, and additional offices in Gangnam and Daegu, South Korea, serving both US and international markets.

Ceribell develops point-of-care EEG systems for rapid seizure detection and monitoring in critical care settings. The company's flagship product, a portable EEG platform integrated with the CLARITY® AI algorithm, enables bedside detection of seizure activity, including non-convulsive seizures, in ICUs, emergency departments, and neurology units. CLARITY® is FDA-cleared for pediatric and neonatal patients, representing the first and only FDA-cleared seizure detection algorithm for newborns preterm and up. The system delivers 95% sensitivity and 97% specificity for status epilepticus detection with 99.9% negative predictive value. Ceribell's secure cloud portal features FedRAMP High cybersecurity authorization for telemedicine consultation and remote EEG interpretation. Clinical evidence demonstrates the platform is associated with 4.1-day shorter median ICU stays and improved neurological outcomes compared to conventional EEG workflows. The company supports hospitals with ongoing in-person and virtual training. Target markets include intensive care units, emergency departments, and neurology departments in acute-care hospitals. Ceribell holds multiple FDA clearances (510(k)), CE mark certification, and has published 45+ peer-reviewed publications validating diagnostic accuracy and clinical utility in critical care populations.

Universal Brain Inc. develops a medical-grade EEG system designed for precision psychiatry, focusing on objective, brain-based diagnosis and treatment of psychiatric conditions, primarily depression. The company has engineered a next-generation EEG wearable headset that captures event-related potentials (ERPs)—brain responses to cognitive and emotional stimuli—and pairs it with Neurotique™, a proprietary digital interface and AI-driven software algorithm that translates raw EEG data into actionable clinical insights. The platform enables neurotyping: the classification of patients based on functional brain measures derived from EEG, allowing clinicians to identify subtypes of psychiatric disorders and tailor treatment accordingly. Universal Brain's approach addresses the heterogeneity of psychiatric conditions by examining core neural systems including attention, memory, and emotional processing. The system is currently investigational and intended for use in clinical settings to aid treatment decision-making and support psychiatric clinical drug trials. The company's leadership includes a psychiatrist founder/CEO (Kazu Okuda, M.D.) and Chief Scientist with expertise in clinical neuroscience (Greg Hajcak, Ph.D.), indicating strong research-clinical integration. The platform represents a shift toward objective, neurobiological markers rather than symptom-based diagnosis alone.

BIO PROTECH, INC. is a medical device manufacturer specializing in surgical instrumentation, patient monitoring electrodes, and therapeutic devices for intraoperative and diagnostic applications. The company produces surgical smoke evacuation systems including smoke pencils (telescopic, economy, dual extension), surgical pencils, smoke adapters, and laparoscopic accessories, along with electrosurgical unit (ESU) plates. In cardiology, BIO PROTECH manufactures ECG electrodes, TAB electrodes, neonatal electrodes, and SpO2 sensors for patient monitoring. The neurology product line includes EMG needles and electrodes, EEG cup electrodes, surface electrodes, intraoperative neuromonitoring (IONM) needles, and neurology cables. Pain management offerings encompass TENS (transcutaneous electrical nerve stimulation) electrodes and TENS units, as well as EMS (electrical muscle stimulation) and interferential (IF) therapy units. The company serves global markets with manufacturing and distribution capabilities, operating sales offices in both North America (Cerritos, CA) and South Korea, with support for Europe, Middle East, Asia, South America, Oceania, and Africa. Products are designed to meet global quality standards for surgical, diagnostic, and therapeutic applications across multiple medical specialties.

CGX, LLC is a global leader in mobile EEG technology, specializing in the design and manufacture of advanced dry EEG headsets for physiological data acquisition. The company develops state-of-the-art wearable biosignal acquisition systems featuring dry electrode technology, LED impedance indicators, and long battery life. Their flagship products—the Quick-32r (32-channel) and Quick-20r v2 (21-channel) headsets—are fully integrated with Brain Products' BrainVision Recorder software and are deployed across leading research institutions, including UCSD, University of Chicago, and major pharmaceutical companies. CGX systems are designed for ease of use, comfort, and signal quality in clinical research, sleep scoring, and neuroscience applications.

BIOPAC Systems, Inc. designs and manufactures modular, integrated life science data acquisition and analysis systems for research, education, and human insights applications. The company specializes in high-fidelity measurement of physiological signals including electrocardiography (ECG), electroencephalography (EEG), electromyography (EMG), electrodermal activity (EDA), blood pressure, impedance cardiography, and specialized measures such as functional near-infrared spectroscopy (fNIRS) and laser Doppler flow. BIOPAC systems operate in laboratory, MRI, and real-world/field environments with both wired and wireless data logging capabilities. The company serves three primary markets: academic research (human and animal studies, neuroscience, cardiology, psychophysiology), educational institutions (undergraduate and graduate teaching labs across multiple disciplines), and commercial/human insights applications (consumer research, neuromarketing, product development). Products include the AcqKnowledge software platform for data acquisition and analysis, modular hardware units, and the Biopac Student Lab System with integrated curriculum. Systems support advanced signal processing including heart rate variability analysis, automated ECG/EEG/EMG analysis, event-related potentials (ERP), and cognitive state assessment. BIOPAC is cited in over 58,600 peer-reviewed studies. The company provides extensive support through technical specialists, knowledge bases, application notes, webinars, hands-on workshops, and user manuals for both proprietary and third-party hardware integration.

Gereonics Inc. manufactures specialized biomedical sensors and electrodes for diagnostic and research applications. The company specializes in EEG (electroencephalography) electrodes and systems, including their proprietary Free-Cap EEG Net for non-invasive brain activity monitoring. Product portfolio includes biopotential electrodes for multi-channel physiological signal acquisition and piezoelectric respiratory sensors featuring low-cost, low-profile beltless/adhesive designs using PVDF technology. These sensors are used in sleep studies, clinical diagnostics, and research settings. The company serves hospitals, sleep laboratories, research institutions, and clinical facilities requiring portable and reliable signal acquisition devices. Manufacturing capabilities include custom electrode designs and respiratory sensor configurations. Gereonics operates as a US-based medical device supplier with distribution to clinical and research markets. Products are designed for ease of use, patient comfort, and accurate signal fidelity in demanding diagnostic environments.