Clinical Software in Ohio

Prentke Romich Company (PRC-Saltillo) is a global leader in augmentative and alternative communication (AAC) technology with nearly 60 years of experience. The company designs and manufactures speech-generating devices and communication software for individuals with speech and language impairments. Primary product lines include dedicated AAC devices (Accent, NovaChat, Via), communication apps (LAMP Words for Life, TouchChat, Unity AAC, Dialogue), and proprietary vocabularies (Minspeak, WordPower, Essence). The company also offers multiple access methods including eye tracking, head tracking, and switch-based controls, plus iPad accessories (Versa). Beyond hardware and software, PRC-Saltillo provides comprehensive training (AAC Learning Journey, Minspeak Academy, coaching), implementation support (AAC Language Lab, Realize Language), and consulting services to help users optimize communication outcomes. The organization holds ISO 9001 certification and is accredited by ACHC; it is an ASHA CE-approved provider and ATIA member. The company serves individuals across developmental, acquired, and progressive speech conditions, including autism and aphasia populations, and maintains a global presence with operations in multiple countries.

Codonics, Inc. is a Cleveland-based medical technology innovator specializing in patient safety and medication management solutions. Founded in 1982, the company has deployed over 60,000 installations across more than 110 countries. The Safe Label System (SLS)—Codonics' flagship product—enhances medication safety through real-time barcode scanning and automated labeling at the point of care, reducing administration errors and ensuring TJC and ISMP compliance. SLS integrates seamlessly with anesthesia drug carts and pharmacy workflows across operating rooms, intensive care units, patient floors, and pharmacy departments. Additional offerings include the SLS-Wave (hands-free scanning), Safe Waste System (controlled substance tracking), WasteLog (waste verification), and SLS Administration Tool (formulary management). Recognized as a Top 100 Healthcare Technology Company of 2024 and awarded Medication Safety Technology Company of the Year 2025, Codonics delivers solutions that streamline clinical workflows, improve charge capture, ensure 340B compliance, and prevent medication errors in perioperative and procedural settings.

Monitored Therapeutics, Inc. is a clinical software and remote patient monitoring platform company specializing in lab-quality respiratory diagnostics and physiological data capture. The company develops decentralized clinical trial solutions and healthcare provider platforms that enable at-home and in-clinic patient monitoring with spirometry and other respiratory assessments. Their primary offering supports both clinical research (including respiratory site solutions) and chronic disease management for healthcare systems. The platform integrates real-time data collection, analytics, and clinical insights for monitoring patients remotely while maintaining laboratory-grade quality and compliance standards. Key customers include major academic medical centers and health systems such as Mayo Clinic, Johns Hopkins, Cleveland Clinic, and others. The company serves pharmaceutical sponsors conducting decentralized trials, respiratory sites requiring standardized testing equipment, and healthcare providers managing patients with respiratory conditions requiring home-based monitoring and longitudinal data collection.

Band Connect is an FDA Class II 510(k) Exempt medical device company providing an evidence-based hybrid therapy platform for orthopedic rehabilitation. The company develops sensor-enabled connected exercise equipment paired with a clinician-directed, gamified mobile application that extends in-clinic physical therapy into the home environment. The platform enables licensed physical therapists to manage patient rehabilitation journeys remotely, monitor at-home compliance, and guide patients through personalized resistance-based exercise protocols without cameras or on-body sensors. The system leverages clinically validated resistance training pathways and provides real-time biofeedback to patients while allowing clinicians to make informed clinical decisions based on documented home therapy adherence. Band Connect addresses the sustainability challenge in orthopedic rehabilitation by reducing clinic visit frequency dependencies and improving patient compliance. The company is HIPAA-compliant and has signed the American Physical Therapy Association (APTA) Digital Transparency pledge, committing to the requirement that all digital physical therapy services are performed or directed exclusively by licensed physical therapists in accordance with APTA Standards of Practice. Supported by institutional partners including University of Cincinnati, UC Health, Bon Secours Mercy Health, Cedars-Sinai Health System, and venture backing from Jumpstart Ventures and Techstars, Band Connect serves physical therapy clinics, orthopedic practices, and health systems seeking to optimize patient outcomes and operational efficiency in rehabilitation medicine.

LainaHealth is a virtual physical therapy platform that delivers remote rehabilitation care guided by licensed physical therapists, supported by Laina, a voice-enabled AI care assistant. The platform is designed for patients to access personalized recovery programs on any personal device, anytime, removing traditional barriers to physical therapy access. Services include Virtual Physical Therapy ($150–$250/month) and Outcomes Collection ($5/collection), both integrated with physician and payor networks. The company emphasizes a human-centered approach where technology amplifies clinician-patient relationships rather than replacing them. Key features include 100% digital enrollment, secure text-message delivery of care plans, real-time clinician communication, 1:1 therapist support, and automated patient-reported outcome measures (PROMs) and functional data collection. The platform is HIPAA-compliant and FDA-registered. LainaHealth reports clinical outcomes including 2X session completion rates and 50%+ cost savings compared to traditional physical therapy models across commercial, employer, and government payors. Target conditions treated include chronic back pain, knee pain, hand pain, and post-injury recovery. The company integrates outcomes tracking via automated SMS distribution and API access for data.

UGen Health manufactures wearable devices with integrated software for remote patient monitoring, assessment, and rehabilitation guidance. The platform delivers real-time, form-based movement tracking and personalized feedback for orthopedic recovery in clinical and home settings. Primary applications include rotator cuff physical therapy, conservative management, and pre-rehabilitation protocols, with planned expansion to ACL reconstruction and total knee replacement programs. UGen devices track motion with clinical accuracy via wearables and provide immediate audio and visual cues to ensure proper form and range of motion. Treatment plans are prescribed by licensed healthcare providers and delivered through the UGen mobile application, enabling remote professional guidance throughout recovery. The company holds multiple US patents (US11325000B2, US11779808B2, US11007406B2) and operates as a regulated medical device under FDA jurisdiction as an Rx-only device. Key hospital and health system partners include Akron Children's Hospital, Southwoods Health, and University Hospitals. UGen combines wearable hardware, motion-sensing technology, and software-as-a-service delivery to improve patient outcomes, operational efficiency, and access to rehabilitation services.

Blue Spark Technologies is a Cleveland-based digital health technology company specializing in clinical-grade wearable remote patient monitoring (RPM) solutions. The company develops continuous vital sign monitoring platforms designed to improve standard of care in hospital settings and enhance data collection in clinical trials. Their primary product lines include TempTraq, a wearable patch technology for early fever detection and continuous temperature monitoring, and VitalTraq, a multi-vital remote patient monitoring platform for tracking multiple physiological parameters. The company's solutions are positioned for acute care environments, hospital networks, and clinical trial applications, with demonstrated use cases in oncology trials. Blue Spark Technologies emphasizes clinical-grade accuracy and real-time data transmission capabilities. The company is headquartered in Westlake, Ohio, and maintains a board of advisors with clinical and healthcare technology expertise. Their technology addresses the growing clinical need for accurate, continuous patient monitoring to support early intervention and improve outcomes.

Enable Injections is a healthcare innovation company headquartered in Cincinnati, Ohio, specializing in the development and manufacturing of wearable drug delivery platforms. The company's flagship product is enFuse, a hands-free subcutaneous injection device designed to deliver large medication volumes without intravenous administration. enFuse represents a paradigm shift in patient treatment experience, offering painless, convenient at-home delivery with integrated smart technology capabilities. The company manufactures enFuse in three configurations: wearable injectors, transfer systems for pharmaceutical partners, and smart-enabled versions with digital companion solutions. Enable Injections' commercial product portfolio includes the EMPAVELI Injector, which has received regulatory approval in multiple markets including Saudi Arabia. The company operates manufacturing facilities and maintains partnerships with major pharmaceutical companies including Roche, Sanofi, Apellis, CSL, Incyte, SOBI, Serina, and Viridian Therapeutics for clinical trials and joint commercial launches. Manufacturing capabilities are located in Springdale, Ohio, with business administration and innovation centers in West Chester, Ohio. The platform has received industry recognition from publications such as Fierce Pharma and PM360 for innovative technology and patient-centric design. Enable Injections has secured significant capital investment, including a $30 million funding round from Sanofi announced in January 2026 to accelerate manufacturing capabilities. The company focuses on improving patient quality of life through simplified medication delivery, particularly for chronic disease management requiring frequent or large-volume injections.

Estone Technology is a global ODM/OEM designer and manufacturer of rugged computing devices for medical, industrial, military, and mission-critical applications. With over 20 years of expertise, the company specializes in custom-built rugged tablet PCs, medical-grade tablets, industrial panel PCs, HMI systems, and embedded computing solutions. Medical product lines include the EN-150 (15.6" AI-enabled tablet for endoscopy, X-ray, and ultrasound image processing), MJ-80 (8" medical rugged tablet), and MD-100 (10.1" medical tablet). Industrial offerings encompass HMI control panels (HMI-70, HMI-1500) and panel PCs (PPC-4107) designed for cleanroom and automated manufacturing environments. Rugged product line includes the UR-100N (10.1" Windows tablet), MS-100A (10.1" Android tablet), and MJ-60 (6" handheld). The company provides full-stack ODM/OEM services: hardware design and PCB engineering, software development (MDM/RDM, application, OS/firmware), device management systems, and AI integration. Estone devices meet MIL-STD-810G/H (environmental durability), MIL-STD-461G (electromagnetic compatibility), and IP67/IP68 waterproofing standards. Additional technologies include RFID integration, CAC/smart card readers, and Ultra-Wideband (UWB) connectivity. Estone operates global offices in the US (Toledo, OH headquarters; Walnut, CA), Europe (Eindhoven, Netherlands), Japan, and China, serving healthcare, industrial automation, logistics, military, and smart agriculture sectors.

Right Way Medical is a US-based medical device distributor specializing in infusion pumps, disposables, biomedical services, and asset-tracking software for post-acute healthcare providers. The company distributes volumetric and enteral feeding pumps from manufacturers including Fresenius Kabi (Agilia Connect), Amsino (Puggle), Smith Medical (CADD SOLIS VIP), and Eitan (Sapphire Multi-Therapy System). Beyond product distribution, Right Way Medical offers comprehensive biomedical repair and maintenance services for medical equipment. The company developed Right Track, a proprietary asset-tracking software platform designed to minimize human error and streamline inventory management and equipment compliance for healthcare facilities. Right Way Medical operates multiple regional offices across the United States (Arizona, Texas, Illinois, Georgia, Pennsylvania) and serves post-acute care settings, pharmacies, and specialty medical product companies. The company maintains partnerships with numerous leading medical device manufacturers and has built relationships with major healthcare organizations since at least 2014. Services are characterized by direct account management, responsive support, and customized solutions tailored to provider needs.

Strolll Limited develops Reality DTx®, a digital therapeutic software platform for augmented reality (AR) glasses designed for neurorehabilitation. The solution uses transparent, see-through AR lenses that blend digital content with physical space, enabling clinicians to deliver immersive therapy in real-world environments—clinic or home. The platform captures objective, clinically relevant data during both in-clinic and at-home rehabilitation sessions, supporting remote monitoring and automated clinical documentation. Strolll integrates into existing clinical workflows for synchronous or asynchronous therapy delivery, reducing administrative burden while enabling real-time patient oversight. The platform addresses gait training, mobility improvement, fall prevention, and functional recovery across neurological conditions including Parkinson's disease, stroke, and generalized balance disorders. Regulatory credentials include CE marking, UKCA certification, FDA clearance, NHS Data Security and Protection Toolkit (DTAC) compliance, and DCB0129 designation. The company collaborates with NHS facilities, private rehabilitation centers, physiotherapy practices, and academic institutions across the UK and US. Target users are physical therapists, occupational therapists, and rehabilitation specialists managing both outpatient and home-based programs.

DEM Medical (PADCO Holding Company) is a turnkey product development and contract manufacturing firm specializing in FDA-compliant, ISO 13485:16-certified medical device manufacturing. Founded in 1993 and based in the USA, DEM provides end-to-end design, engineering, and manufacturing services for the medical device industry, with capabilities spanning printed circuit board assemblies (PCBA), custom cabling and connectors, injection molding, 3D printing and rapid prototyping, and tooling design. The company is vertically integrated—all design, engineering, and production occur in-house—enabling rapid prototyping (as little as 10 weeks from concept to prototype), transparent pricing, and rigorous quality assurance. DEM holds ITAR, ISO 9001:15, ISO 13485:16, IPC-620, FDA Class II, REACH, and RoHS certifications. The firm serves medical device OEMs, startups, and innovators requiring custom, low-to-high-volume production with dependable delivery schedules and compliance-ready solutions.

Spot Health is a B2B platform provider specializing in at-home laboratory testing solutions for health brands, wellness companies, and telehealth platforms. The company operates a turnkey service that enables third-party brands to offer lab-analyzed blood, urine, and saliva tests with at-home sample collection under their own branding. Spot Health manages end-to-end logistics, including kit distribution, sample collection coordination, prepaid shipping to partner laboratories, and results integration into customer-facing applications. The platform handles regulatory compliance including state-level physician order requirements where applicable and maintains HIPAA compliance. Spot Health partners with established clinical laboratories for test analysis and provides medically-vetted result interpretations alongside normal ranges for seamless integration into client applications. The platform supports diverse use cases including personalized product recommendations (supplements, fitness programs, meal plans), chronic condition monitoring, cancer and STI screening, and efficacy studies for consumer health products. Key features include rapid deployment (launch in days rather than months), white-label customization to match client branding, and comprehensive documentation and API support for integration. Spot Health positions itself as infrastructure for the remote care and at-home diagnostics market, targeting health tech companies, telehealth platforms, and consumer wellness brands seeking to add laboratory testing capabilities without building proprietary lab operations.

Capsa Healthcare is a 60+ year-old medical equipment and healthcare solutions company specializing in pharmacy automation, medication management, point-of-care technologies, and health IT infrastructure. The company manufactures and distributes medical computer workstations (Trio, V6), automated medication dispensing cabinets (NexsysADC), pharmacy automation systems including central fill and mail-order pharmacy solutions, Kirby Lester pill counters and tablet counters (KL1v), endoscope drying cabinets (TruAir), crash carts (Avalo), and mobile computing stands. Capsa's solutions are designed to optimize clinical workflows, streamline medication management, and improve operational efficiency across acute care hospitals, extended care facilities, retail and institutional pharmacies. The company claims 60% market adoption among U.S. pharmacies, 70% hospital reliance on workstations, and 80% adoption in institutional pharmacies. Products span emergency departments, ICUs, operating rooms, radiology, gastroenterology, patient rooms, and pharmacy operations. Capsa offers integrated end-to-end solutions combining hardware, software, and workflow optimization. The company provides service and support, product manuals, case studies, and white papers. Recently acquired BlueBin for intelligent clinical supply management and unveiled a Consolidated Services Pharmacy Platform (CSPP).

Pro2Health manufactures PrO2, a cloud-connected respiratory muscle training (RMT) system for healthcare, fitness, and research applications. The company's proprietary TIRE (Threshold Inspiratory Resistance Exercise) methodology delivers full-breath resistance training to strengthen the diaphragm and intercostal muscles. The platform comprises professional-grade handheld devices, native iOS/Android mobile applications, Windows-based clinician dashboards, and HIPAA-aligned cloud infrastructure for remote monitoring and data analytics. Devices are FDA registered and CE marked. The system supports multi-user operation via disposable filters, real-time biofeedback, and wireless charging on select models. Clinical applications include COPD, heart failure, asthma, Long-COVID, and 15+ additional respiratory and cardiovascular conditions validated across 40+ peer-reviewed studies spanning 25+ years of research. The platform offers CPT code support for reimbursement, clinician mode for patient customization and progress tracking, and IRB-compliant protocols for research deployments. Fitness applications target endurance, VO2 max optimization, and athletic performance enhancement. Subscription tiers provide unlimited data storage, analytics, and multi-site management for clinics and research institutions. Raw data export and API access available for research partners. The company serves healthcare professionals, athletes, trainers, patients, and researchers globally.

HemaSource is a specialized logistics and supply chain solutions provider serving high-volume ambulatory care clinics, with particular expertise in plasma collection centers, renal dialysis facilities, blood transfusion services, and IV hydration/infusion centers. The company operates as a disposables distributor and 3PL (third-party logistics) service provider, combining proprietary web-based ordering and inventory management software with a curated catalog of medical consumables and related equipment. The company's core offering centers on its patented ACE™ software platform—a customizable, cloud-based analytics and ordering system designed to auto-calculate inventory requirements, optimize usage patterns, reduce waste, and drive cost savings across distributed multi-center healthcare operations. The software provides center-level visibility into consumption metrics and supports compliance with regulatory requirements. HemaSource supplies an expansive catalog of high-quality medical disposables, with documented expertise in exam gloves, blood collection supplies, renal therapy consumables, and acute care products. The company serves primarily US markets (Northeast, Southeast, Midwest, Southwest, and West regions) with additional European operations. The organization brings over 100 years of combined industry experience and positions itself as a preferred partner to specialty ambulatory clinics seeking operational efficiency gains and per-unit cost reduction through data-driven inventory optimization and supply chain management.

JETA Molecular BV is a molecular diagnostics company specializing in transplantation medicine, with particular focus on post-transplant monitoring solutions. The company develops and commercializes in vitro diagnostic (IVD) assays and software for early detection of transplant rejection and disease relapse following hematopoietic stem cell transplantation (HSCT) and solid organ transplantation. Core product lines include QTRACE® chimerism analysis systems utilizing quantitative PCR (qPCR) technology with 80 INDEL assays for recipient-derived white blood cell monitoring, DigitalTRACE™ digital PCR (dPCR) assays for sensitive chimerism detection, and HLA TRACE™ assays for detecting HLA loss of heterozygosity (LOH) post-HSCT. The company also offers TRACE Analysis™ software for qPCR data analysis, protocol generation, longitudinal sample tracking, and LIMS integration. JETA's solutions enable clinicians to adjust immunosuppression regimens, optimize graft survival, and improve patient outcomes. The company was founded by researchers with extensive expertise in IVD/CE-marked assay development, ASR/GPR designation, and RUO molecular diagnostic kits for transplantation and human genetic testing. JETA maintains collaborations with key opinion leaders in stem cell and solid organ transplantation. The company operates as a European entity based in Utrecht, The Netherlands, with product distribution through established diagnostic partners.

Surgical Theater, Inc. develops eXperiential Reality (XR) platforms that transform 2D medical imaging (MRI, CT, DTI) into interactive 3D surgical models using AI-driven reconstruction technology. The company serves neurosurgery, spine surgery, and otolaryngology specialties with three primary solutions: PlanXR™ for preoperative surgical planning and rehearsal; Brain STORM™ for epilepsy care management; and SyncAR® (Spine and Cranial variants) for real-time intraoperative augmented reality visualization. Additional products include XR Studio™ for multidisciplinary case reviews and education within XR headsets, and ConveyXR™ for patient engagement and informed consent. The platform enables surgeons to visualize patient-specific anatomy, identify critical structures (nerves, blood vessels), and simulate complex procedures before entering the operating room. Deployed at leading academic medical centers including Mayo Clinic, Stanford, Mount Sinai, Houston Methodist, UCSF, and NYU Langone, among others. The technology derives from advanced flight simulation methodologies applied to surgical visualization. Regulatory status and specific FDA clearances not explicitly stated on fetched content, though clinical research studies referenced. Serves both academic and community hospital markets internationally.